Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14286140 | 0.98 | HTR2C (0.36) | HTR2CNAAADGKAKMT2APRSS1 | |
| SCHEMBL14048718 | 0.89 | NAAA (0.47) | HTR2CNAAADGKAPRSS1PRSS2 | |
| SCHEMBL14344628 | 0.87 | NAAA (0.44) | HTR2CNAAADGKAPRSS1PRSS2 | |
| SCHEMBL17472303 | 0.84 | CYP19A1 (0.31) | — | |
| SCHEMBL13729179 | 0.84 | HTR2C (0.36) | HTR2CNAAADGKAPRSS1PRSS2 | |
| SCHEMBL14472726 | 0.82 | NAAA (0.40) | HTR2CNAAADGKAPRSS1PRSS2 | |
| SCHEMBL15385418 | 0.82 | DGKA (0.46) | DGKAKMT2AMAPTDNM1 | |
| SCHEMBL14308492 | 0.82 | CA1 (0.44) | HTR2CNAAADGKAKMT2APRSS1 | |
| SCHEMBL6439025 | 0.80 | NAAA (0.60) | HTR2CNAAADGKAPRSS1PRSS2 | |
| SCHEMBL889159 | 0.80 | NAAA (0.60) | HTR2CNAAADGKAPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903068-A1 | Biodegradable poly(beta-amino esters) and uses thereof | Massachusetts Institute of Technology (MIT) (US) | 2008-03-26 | — | — | EP | disclosed |