Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048718 | 0.98 | NAAA (0.47) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL14472726 | 0.94 | NAAA (0.40) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL14286140 | 0.88 | HTR2C (0.36) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL14286142 | 0.87 | HTR2C (0.39) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL14565821 | 0.85 | DGKA (0.46) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL28718240 | 0.84 | DGKA (0.59) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL2622471 | 0.83 | DGKA (0.44) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL14018445 | 0.82 | HTR2C (0.39) | NAAADGKAHTR2CADRA2AADRA1A | |
| SCHEMBL21226023 | 0.81 | DGKA (0.47) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL18862484 | 0.81 | HRH2 (0.41) | NAAADGKAHTR2CADRA1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007143659-A2 | CROSSLINKED, DEGRADABLE POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-12-13 | — | — | WO | disclosed |