SCHEMBL1404929

SCHEMBL1404929

CC(=O)C=Cc1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 1.00
LMNA P02545 1/20 1.00
IAPP P10997 1/20 0.72
NFKB1 P19838 2/20 0.70
JUN P05412 1/20 0.70
NFE2L2 Q16236 1/20 0.70
CA1 P00915 1/20 0.68
CA2 P00918 1/20 0.68
CA4 P22748 1/20 0.68
BCHE P06276 1/20 0.61
GUSB P08236 1/20 0.61
KDM4E B2RXH2 2/20 0.59
TDP1 Q9NUW8 2/20 0.57
MAPK1 P28482 2/20 0.57
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
ATM Q13315 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
CHRNA7 P36544 3/20 0.56
GLA P06280 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377511 1.00 MAPT (1.00) MAPTLMNAIAPPNFKB1JUN
SCHEMBL1404928 1.00 MAPT (1.00) MAPTLMNAIAPPNFKB1JUN
SCHEMBL29428452 1.00 MAPT (1.00) MAPTLMNAIAPPNFKB1JUN
SCHEMBL14441077 0.87 MAPT (0.76) MAPTLMNAIAPPNFKB1JUN
SCHEMBL26046362 0.84 IAPP (1.00) MAPTLMNAIAPPNFKB1JUN
SCHEMBL7177478 0.84 IAPP (1.00) MAPTLMNAIAPPNFKB1JUN
SCHEMBL29539991 0.83 NFKB1 (1.00) MAPTLMNANFKB1JUNNFE2L2
SCHEMBL1160535 0.83 NFKB1 (1.00) MAPTLMNANFKB1JUNNFE2L2
SCHEMBL1160537 0.83 NFKB1 (1.00) MAPTLMNANFKB1JUNNFE2L2
SCHEMBL3329177 0.83 NFKB1 (1.00) MAPTLMNANFKB1JUNNFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114870894-B Nickel-based catalyst derived from self-supporting layered double hydroxide, and preparation method and application thereof 浙江新化化工股份有限公司 2023-11-03 CN claimed
CN-114890975-B Compound with fused ring chroman structure and preparation method thereof 合肥工业大学 2023-07-18 CN claimed
CN-114634465-B Pentadienone derivative containing sulfonyl piperazine as well as preparation method and application thereof 贵州大学 2023-05-30 CN claimed
CN-114890975-A Compound with parachroman structure and preparation method thereof 合肥工业大学 2022-08-12 CN claimed
CN-109134399-B Benzothiazole-containing 1, 4-pentadiene-3-ketone derivative, and preparation method and application thereof 贵州大学 2022-04-26 CN claimed
CN-109721559-B 1, 4-pentadiene-3-ketone derivative containing thioether triazole, preparation method and application 贵州大学 2022-02-15 CN claimed
EP-3413906-B1 CANCER TREATMENT COMBINATION COMPOSITIONS, METHODS AND USES UNIV LOUISIANA STATE (US) 2021-10-27 EP claimed
CN-108822045-B Quinazoline-containing 1, 4-pentadiene-3-ketoxime ether derivative, preparation method and application 贵州大学 2021-06-08 CN claimed
CN-109721559-A A kind of 1,4- pentadiene -3- ketones derivant, the Preparation method and use of Sulfide-containing Hindered triazole 贵州大学 2019-05-07 CN claimed
CN-109134399-A A kind of Isosorbide-5-Nitrae containing benzothiazole-pentadiene -3- ketones derivant, preparation method and application 贵州大学 2019-01-04 CN claimed
EP-1534227-A1 AGENTS USED FOR DYEING KERATINOUS FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2005-06-01 EP claimed
WO-2004058202-A1 DYE TABLETS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-07-15 WO claimed
WO-2004058200-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-07-15 WO claimed
EP-1434557-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2004-07-07 EP claimed
EP-1433469-A1 Composition for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
WO-2004022016-A1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-03-18 WO claimed
WO-2003030845-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-0873743-A2 Use of benzylidene-ketones for dyeing keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP claimed
EP-0738143-A1 CURCUMIN, ANALOGUES OF CURCUMIN AND NOVEL USES THEREOF RESEARCH DEVELOPMENT FOUNDATION (US) 1996-10-23 EP claimed
WO-1995018606-A1 CURCUMIN, ANALOGUES OF CURCUMIN AND NOVEL USES THEREOF RESEARCH DEVELOPMENT FOUNDATION (US) 1995-07-13 WO claimed