Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | ERN1 | O75460 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26046362 | 1.00 | IAPP (1.00) | IAPPLMNAMAPTERN1BACE1 | |
| SCHEMBL29428452 | 0.84 | MAPT (1.00) | IAPPLMNAMAPTKDM4ENFKB1 | |
| SCHEMBL1404929 | 0.84 | MAPT (1.00) | IAPPLMNAMAPTKDM4ENFKB1 | |
| SCHEMBL1404928 | 0.84 | MAPT (1.00) | IAPPLMNAMAPTKDM4ENFKB1 | |
| SCHEMBL29377511 | 0.84 | MAPT (1.00) | IAPPLMNAMAPTKDM4ENFKB1 | |
| SCHEMBL1404990 | 0.83 | IAPP (0.71) | IAPPLMNAMAPTBACE1KDM4E | |
| SCHEMBL1404989 | 0.83 | IAPP (0.71) | IAPPLMNAMAPTBACE1KDM4E | |
| SCHEMBL307296 | 0.82 | NFKB1 (0.71) | IAPPLMNAMAPTERN1BACE1 | |
| SCHEMBL31083592 | 0.82 | NFKB1 (0.71) | IAPPLMNAMAPTERN1BACE1 | |
| SCHEMBL31256670 | 0.82 | NFKB1 (0.71) | IAPPLMNAMAPTERN1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200129450-A1 | COMPOSITION COMPRISING OSMUNDACETONE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF FOR PREVENTING OR TREATING BONE DISEASE | KORPHARM CO LTD (KR) | 2020-04-30 | — | — | US | disclosed |
| EP-0726074-B1 | METHOD FOR OBTAINING APOLAR AND POLAR EXTRACTS OF CURCUMA AND APPLICATIONS THEREOF | A C PHARMACEUTICAL INTERNATION (ES) | 2003-06-25 | — | — | EP | disclosed |
| US-6440468-B1 | SUBJECTING POWDERED CURCUMA LONGA RHIZOMES TO SOLVENT EXTRACTION TO OBTAIN APOLAR EXTRACT, EXTRACTING WITH WATER TO OBTAIN POLAR EXTRACT, MIXING EXTRACTS | A.S.A.C. PHARMACEUTICAL INTERNATIONAL, A.I.E. (ES) | 2002-08-27 | — | — | US | disclosed |
| EP-0726074-A1 | METHOD FOR OBTAINING APOLAR AND POLAR EXTRACTS OF CURCUMA AND APPLICATIONS THEREOF | A.S.A.C. PHARMACEUTICAL INTERNATIONAL, A.I.E. (ES) | 1996-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200129450-A1 | COMPOSITION COMPRISING OSMUNDACETONE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF FOR PREVENTING OR TREATING BONE DISEASE | SOST, SLC10A6, OSTC | IAPP 2006/4885LMNA 3786/4885MAPT 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.