Sugi Predict

Sugi Predict / Compounds / SCHEMBL1404928

SCHEMBL1404928

SCHEMBL1404928

CC(=O)/C=C/c1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 1.00
▸ LMNA P02545 1/20 1.00
▸ IAPP P10997 1/20 0.72
▸ NFKB1 P19838 2/20 0.70
▸ JUN P05412 1/20 0.70
▸ NFE2L2 Q16236 1/20 0.70
▸ CA1 P00915 1/20 0.68
▸ CA2 P00918 1/20 0.68
▸ CA4 P22748 1/20 0.68
▸ BCHE P06276 1/20 0.61
▸ GUSB P08236 1/20 0.61
▸ KDM4E B2RXH2 2/20 0.59
▸ TDP1 Q9NUW8 2/20 0.57
▸ MAPK1 P28482 2/20 0.57
▸ NPC1 O15118 1/20 0.57
▸ RAB9A P51151 1/20 0.57
▸ ATM Q13315 1/20 0.57
▸ NPSR1 Q6W5P4 1/20 0.57
▸ CHRNA7 P36544 3/20 0.56
▸ GLA P06280 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377511 1.00 MAPT (1.00) MAPTLMNAIAPPNFKB1JUN
SCHEMBL29428452 1.00 MAPT (1.00) MAPTLMNAIAPPNFKB1JUN
SCHEMBL1404929 1.00 MAPT (1.00) MAPTLMNAIAPPNFKB1JUN
SCHEMBL14441077 0.87 MAPT (0.76) MAPTLMNAIAPPNFKB1JUN
SCHEMBL26046362 0.84 IAPP (1.00) MAPTLMNAIAPPNFKB1JUN
SCHEMBL7177478 0.84 IAPP (1.00) MAPTLMNAIAPPNFKB1JUN
SCHEMBL29539991 0.83 NFKB1 (1.00) MAPTLMNANFKB1JUNNFE2L2
SCHEMBL1160535 0.83 NFKB1 (1.00) MAPTLMNANFKB1JUNNFE2L2
SCHEMBL1160537 0.83 NFKB1 (1.00) MAPTLMNANFKB1JUNNFE2L2
SCHEMBL3329177 0.83 NFKB1 (1.00) MAPTLMNANFKB1JUNNFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114890975-B Compound with fused ring chroman structure and preparation method thereof 合肥工业大学 2023-07-18 — — CN claimed
CN-114890975-A Compound with parachroman structure and preparation method thereof 合肥工业大学 2022-08-12 — — CN claimed
CN-109721559-B 1, 4-pentadiene-3-ketone derivative containing thioether triazole, preparation method and application 贵州大学 2022-02-15 — — CN claimed
EP-3413906-B1 CANCER TREATMENT COMBINATION COMPOSITIONS, METHODS AND USES UNIV LOUISIANA STATE (US) 2021-10-27 — — EP claimed
EP-3413906-A1 CANCER TREATMENT COMBINATION COMPOSITIONS, METHODS AND USES The Board of Supervisors of Louisiana State University & Agricultural & Mechanical College (US) 2018-12-19 — — EP claimed
US-20170258929-A1 CANCER TREATMENT COMBINATION COMPOSITIONS, METHODS AND USES BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2017-09-14 — — US claimed
WO-2017139644-A1 CANCER TREATMENT COMBINATION COMPOSITIONS, METHODS AND USES BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2017-08-17 — — WO claimed
EP-2847318-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES Marrone Bio Innovations, Inc. (US) 2015-03-18 — — EP claimed
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES PRO FARM GROUP, INC. 2015-01-29 — — US claimed
WO-2013138398-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES MARRONE BIO INNOVATIONS, INC. (US) 2013-09-19 — — WO claimed
EP-0738143-A1 CURCUMIN, ANALOGUES OF CURCUMIN AND NOVEL USES THEREOF RESEARCH DEVELOPMENT FOUNDATION (US) 1996-10-23 — — EP claimed
WO-1995018606-A1 CURCUMIN, ANALOGUES OF CURCUMIN AND NOVEL USES THEREOF RESEARCH DEVELOPMENT FOUNDATION (US) 1995-07-13 — — WO claimed
CN-115710244-B Preparation method of coumarin 万华化学集团股份有限公司 2024-04-09 — — CN disclosed
US-11746364-B2 Enzymatic synthesis of kavalactones and flavokavains WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2023-09-05 — — US disclosed
US-11739354-B2 Enzymatic synthesis of kavalactones and flavokavains WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2023-08-29 — — US disclosed
CN-114890975-B Compound with fused ring chroman structure and preparation method thereof 合肥工业大学 2023-07-18 — — CN disclosed
WO-1999046266-A1 BENZOXADIAZOCINYL ARTHROPODICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-09-16 — — WO disclosed
WO-1998033385-A1 PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS MONSANTO COMPANY (US) 1998-08-06 — — WO disclosed
US-4859664-A Derivatives of 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonines and -1,4-benzoxazonines, processes for their production and their use as pharmaceuticals MADAUS GMBH & COMPANY (DE) 1989-08-22 — — US disclosed
US-4725628-A Process of making a crosslinked superabsorbent polyurethane foam KIMBERLY-CLARK CORPORATION (US) 1988-02-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170258929-A1 CANCER TREATMENT COMBINATION COMPOSITIONS, METHODS AND USES GNRHR, LHCGR, MKI67 MAPT 3039/4885LMNA 1276/4885IAPP 306/4885
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES BLVRB, PRDX6, ACHE MAPT 3804/4885LMNA 2685/4885IAPP 1262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.