Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14050432 | 0.89 | PTPN11 (0.45) | SLC6A9RARBCNR2RARARARG | |
| SCHEMBL14050505 | 0.85 | SLC6A9 (0.36) | SLC6A9MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL9484389 | 0.83 | MAPT (0.46) | MAPTKDM4EALDH1A1MEN1USP2 | |
| SCHEMBL4602854 | 0.80 | PTPN11 (0.57) | FFAR4RARBRARARARG | |
| SCHEMBL14610579 | 0.79 | PTPN11 (0.44) | MAPTMEN1HTTKMT2AHSD17B10 | |
| SCHEMBL91982 | 0.77 | RARA (0.38) | MAPTKDM4EALDH1A1MEN1USP2 | |
| SCHEMBL14456310 | 0.77 | PTPN11 (0.36) | SLC6A9FFAR4RARBCNR2RARA | |
| SCHEMBL16855902 | 0.76 | CCNT1 (0.38) | MAPTKDM4EALDH1A1MEN1USP2 | |
| SCHEMBL9486073 | 0.75 | THRA (0.51) | RARBRARARARG | |
| SCHEMBL10979559 | 0.75 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1816180-B1 | Mesogenic compounds, liquid crystal medium, and liquid crystal display | MERCK PATENT GMBH (DE) | 2008-10-29 | — | — | EP | disclosed |
| EP-1816180-A1 | Mesogenic compounds, liquid crystal medium, and liquid crystal display | Merck Patent GmbH (DE) | 2007-08-08 | — | — | EP | disclosed |