Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221048 | 0.88 | AADAT (0.48) | AADATTMEM97SIGMAR1GFERNPSR1 | |
| SCHEMBL15503355 | 0.84 | AADAT (0.47) | AADATTMEM97SIGMAR1GFERFKBP1A | |
| SCHEMBL15957792 | 0.82 | SIGMAR1 (0.49) | AADATTMEM97SIGMAR1GFER | |
| SCHEMBL12952997 | 0.81 | SIGMAR1 (0.48) | AADATTMEM97SIGMAR1ALDH1A1PREP | |
| SCHEMBL22176306 | 0.79 | KLK7 (0.41) | AADATTMEM97SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL30311378 | 0.79 | KLK7 (0.41) | AADATTMEM97SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL30311213 | 0.78 | AADAT (0.38) | AADATTMEM97SIGMAR1NPSR1FKBP1A | |
| SCHEMBL15957791 | 0.78 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL30311334 | 0.77 | KLK7 (0.40) | AADATTMEM97SIGMAR1ALDH1A1NPSR1 | |
| SCHEMBL14050894 | 0.77 | AADAT (0.48) | AADATTMEM97SIGMAR1GFERNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809330-B2 | Pyrazolo[1,5-A]pyrimidines for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2014-08-19 | — | — | US | disclosed |