Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500006 | 0.82 | KDM4C (0.38) | NOTUMHRH1HTR6GPR3HDAC4 | |
| SCHEMBL13759056 | 0.81 | MTNR1A (0.35) | MTNR1AMTNR1BNOTUMBRD4CCKBR | |
| SCHEMBL1104628 | 0.79 | MTNR1A (0.34) | MTNR1AMTNR1BNOTUMBRD4CCKBR | |
| SCHEMBL27741771 | 0.79 | NOTUM (0.39) | MTNR1AMTNR1BNOTUMBRD4CCKBR | |
| SCHEMBL2606493 | 0.76 | HRH1 (0.43) | MTNR1AMTNR1BCCKBRHRH1HTR6 | |
| SCHEMBL14543698 | 0.76 | NOTUM (0.64) | NOTUMBRD4HTR2AHTR1ADRD2 | |
| SCHEMBL8264301 | 0.75 | CACNA1G (0.33) | NOTUMBRD4LMNAKDM4EOPRM1 | |
| SCHEMBL8261724 | 0.74 | CYP2C9 (0.40) | LMNAKDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL19387437 | 0.73 | ENPP2 (0.33) | KDM4E | |
| SCHEMBL27787296 | 0.73 | HRH1 (0.32) | NOTUMHRH1HTR6GPR3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | disclosed |