SCHEMBL140535

SCHEMBL140535

CO[Si](OC)(OC)C(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.39
KMT2A Q03164 1/20 0.39
TAAR1 Q96RJ0 3/20 0.38
ALDH1A1 P00352 3/20 0.37
THRB P10828 1/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
CYP2D6 P10635 1/20 0.37
LMNA P02545 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.36
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
FAAH O00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235152 0.87 ESR1 (0.36) TRPA1ALDH1A1
SCHEMBL574711 0.86 HDAC4 (0.38) TAAR1ALDH1A1KDM4EHPGD
SCHEMBL1492150 0.81 HTR2A (0.43) KMT2ATAAR1CYP2D6LMNA
SCHEMBL27147585 0.81 CYP17A1 (0.34) FAAH
SCHEMBL9716601 0.81 KMT2A (0.39) TRPA1KMT2ATAAR1ALDH1A1THRB
SCHEMBL3084097 0.79 FAAH (0.38) TRPA1KMT2ATAAR1ALDH1A1THRB
SCHEMBL6890013 0.79 FAAH (0.38) TRPA1KMT2ATAAR1ALDH1A1THRB
SCHEMBL28793321 0.79 TAAR1 (0.37) TRPA1TAAR1ALDH1A1ADRA2AADRA2C
SCHEMBL760246 0.79 ESR1 (0.52) TAAR1CYP2D6LMNAHIF1AKDM4E
SCHEMBL330049 0.79 CYP3A4 (0.41) KMT2AALDH1A1CYP2D6LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 918 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4592369-A1 UV-CURABLE COATING MATERIAL AND METHOD FOR UV-HARDENING COATING MATERIAL NANO-X GmbH (DE) 2025-07-30 EP claimed
EP-2262576-B1 COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY WATERS TECHNOLOGIES CORP (US) 2025-03-12 EP claimed
CN-117986583-A Preparation method of ultrafine uniform-particle-size polysiloxane microspheres and product thereof 浙江精通科技股份有限公司 2024-05-07 CN claimed
WO-2023122108-A1 SYNTHESIS, CAPPING AND DISPERSION OF HIGH REFRACTIVE INDEX NANOCRYSTALS AND NANOCOMPOSITES PIXELLIGENT TECHNOLOGIES LLC (US) 2023-06-29 WO claimed
US-11426707-B2 Composite materials containing nanoparticles and their use in chromatography WATERS TECHNOLOGIES CORPORATION (US) 2022-08-30 US claimed
CN-114292614-A Preparation method of modified silicon dioxide-epoxy resin composite slurry 西陇科学股份有限公司 2022-04-08 CN claimed
US-11129363-B2 Polymer-based training aids and methods of use THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2021-09-28 US claimed
EP-3792227-A1 COATING MATERIAL FOR PRODUCING A SINGLE STAGE COATING OF CONTAINER GLASS AND ITS USE Wiegand-Glashüttenwerke GmbH (DE) 2021-03-17 EP claimed
CN-111777874-A Nano silicon dioxide and surface modification method thereof 深圳先进技术研究院 2020-10-16 CN claimed
US-20190015815-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A COATED CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION 2019-01-17 US claimed
US-20060171870-A1 PROCESS OF MAKING HYDROPHOBIC METAL OXIDE NANOPARTICLES XEROX CORPORATION (US) 2006-08-03 US claimed
US-7081234-B1 Mixing metal oxide nanoparticles, a solvent, and a surface treatment agent, heating XEROX CORPORATION (US) 2006-07-25 US claimed
US-20050233231-A1 Photoconductive imaging members XEROX CORPORATION 2005-10-20 US claimed
EP-1075544-A4 CHEMICALLY MODIFIED NUCLEIC ACIDS AND METHODS FOR COUPLING NUCLEIC ACIDS TO SOLID SUPPORT BAYLOR COLLEGE MEDICINE (US) 2005-03-09 EP claimed
US-6423770-B1 Silicate material and process for fabricating silicate material LUCENT TECHNOLOGIES INC. 2002-07-23 US claimed
EP-1075544-A1 CHEMICALLY MODIFIED NUCLEIC ACIDS AND METHODS FOR COUPLING NUCLEIC ACIDS TO SOLID SUPPORT BAYLOR COLLEGE OF MEDICINE (US) 2001-02-14 EP claimed
WO-1999057323-A1 CHEMICALLY MODIFIED NUCLEIC ACIDS AND METHODS FOR COUPLING NUCLEIC ACIDS TO SOLID SUPPORT BAYLOR COLLEGE OF MEDICINE (US) 1999-11-11 WO claimed
EP-0579453-B1 Method of preparing a masonry treating composition DOW CORNING (US) 1997-10-08 EP claimed
EP-0579453-A2 Masonry treating composition and method DOW CORNING CORPORATION (US) 1994-01-19 EP claimed
US-5225510-A Hydrolysis of silane monomer in the presence of acid catalysts followed by basic neutralization DOW CORNING CORPORATION (US) 1993-07-06 US claimed