SCHEMBL3084097

SCHEMBL3084097

CO[Si](C)(OC)C(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.38
KMT2A Q03164 1/20 0.38
TAAR1 Q96RJ0 3/20 0.37
ALDH1A1 P00352 2/20 0.36
EPHX1 P07099 1/20 0.36
THRB P10828 1/20 0.36
ADRA2A P08913 1/20 0.35
ADRA2C P18825 1/20 0.35
CYP2D6 P10635 1/20 0.35
LMNA P02545 1/20 0.35
HIF1A Q16665 1/20 0.35
KDM4E B2RXH2 1/20 0.35
TRPA1 O75762 2/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2239550 0.88 ESR1 (0.35)
SCHEMBL2242587 0.86 HDAC4 (0.37) FAAHALDH1A1KDM4E
SCHEMBL6890013 0.82 FAAH (0.38) FAAHKMT2ATAAR1ALDH1A1EPHX1
SCHEMBL3191517 0.80 CHRNA7 (0.37) KMT2AALDH1A1LMNA
SCHEMBL9716601 0.79 KMT2A (0.39) KMT2ATAAR1ALDH1A1THRBADRA2A
SCHEMBL8849269 0.79 KMT2A (0.39) FAAHKMT2AALDH1A1EPHX1THRB
SCHEMBL140535 0.79 TRPA1 (0.39) FAAHKMT2ATAAR1ALDH1A1THRB
SCHEMBL960017 0.79 GABRA1 (0.39) FAAHALDH1A1ADRA2AADRA2CCYP2D6
SCHEMBL7938711 0.77 TAAR1 (0.38) TAAR1ALDH1A1LMNATRPA1
SCHEMBL19809462 0.76 KMT2A (0.41) KMT2AALDH1A1ADRA2AADRA2CCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7794782-B2 Phosphonate and sulfido silane anti-corrosion additive for electrical cable restoration fluid DOW CORNING CORPORATION (US) 2010-09-14 US claimed
JP-63223009-A None JP disclosed
CN-107209303-B Far infrared ray reflective film, dispersion for forming far infrared ray reflective film, method for producing far infrared ray reflective film, far infrared ray reflective glass, and window 富士胶片株式会社 2020-07-14 CN disclosed
CN-1802394-B Polyorganosiloxane-containing graft copolymer, resin composition containing the same, and method for producing polyorganosiloxane emulsion KANEGAFUCHI CHEMICAL IND 2012-05-09 CN disclosed
CN-1950411-A Graft copolymer and resin compositions containing the same KANEGAFUCHI CHEMICAL IND (JP) 2007-04-18 CN disclosed
CN-1802394-A Polyorganosiloxane-containing graft copolymer, resin composition containing the same, and method for producing polyorganosiloxane emulsion KANEGAFUCHI CHEMICAL IND (JP) 2006-07-12 CN disclosed
CN-1802414-A Rubber-modified styrene resin composition KANEGAFUCHI CHEMICAL IND (JP) 2006-07-12 CN disclosed
CN-1768113-A Polyester resin composition KANEGAFUCHI CHEMICAL IND (JP) 2006-05-03 CN disclosed
EP-0671417-B1 Components and catalysts for the copolymerisation of olefins MONTELL NORTH AMERICA INC (US) 1997-05-02 EP disclosed
EP-0437263-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1995-11-08 EP disclosed
EP-0671417-A2 Components and catalysts for the copolymerisation of olefins MONTELL NORTH AMERICA INC. (US) 1995-09-13 EP disclosed
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
US-5106807-A Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific HIMONT INCORPORATED (US) 1992-04-21 US disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
EP-0437263-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-07-17 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
JP-S63223009-A POLYMERIZATION OF OLEFIN MITSUI PETROCHEM IND LTD 1988-09-16 JP disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed