SCHEMBL14059947

SCHEMBL14059947

Cc1cc(C(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)ccc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.43
LPL P06858 12/20 0.42
LIPG Q9Y5X9 12/20 0.42
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
CA9 Q16790 4/20 0.40
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
F11 P03951 2/20 0.39
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
F2 P00734 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28371250 0.83 LIPG (0.57) ESR2LPLLIPGCA1CA2
SCHEMBL60127 0.82 LPL (0.47) LPLLIPGCA1CA2CA9
SCHEMBL30749457 0.78 CYP3A4 (0.54) ESR2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL5166514 0.78 CYP3A4 (0.54) ESR2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL20276718 0.77 LIPG (0.65) ESR2LPLLIPGCA1CA2
SCHEMBL109819 0.75 CYP3A4 (0.46) ESR2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL31409207 0.75 ALDH1A1 (0.46) ESR2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL30602820 0.75 CYP3A4 (0.46) ESR2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL13070208 0.75 ALDH1A1 (0.46) ESR2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL3690091 0.74 LPL (0.46) LPLLIPGCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012160383-A1 TRANSISTORS AND METHODS FOR MAKING THEM THE CENTRE FOR PROCESS INNOVATION LTD (GB) 2012-11-29 WO disclosed