Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17054434 | 0.79 | PGR (0.48) | S100A4PTPRCMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2381810 | 0.79 | ALDH1A1 (0.46) | S100A4PTPRCMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL26959507 | 0.77 | PTPRC (0.46) | S100A4PTPRCMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL18235870 | 0.76 | PDK2 (0.45) | MAPTSMN1; SMN2L3MBTL1ATMPDK2 | |
| SCHEMBL10045382 | 0.75 | PGR (0.51) | S100A4PTPRCMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2791571 | 0.73 | PTPRC (0.56) | S100A4PTPRCMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2381514 | 0.73 | PTPRC (0.56) | S100A4PTPRCMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL13191499 | 0.73 | ALDH1A1 (0.41) | TTRS100A4PTPRCMAPTSMN1; SMN2 | |
| SCHEMBL13045515 | 0.72 | PDK2 (0.52) | PDK2 | |
| SCHEMBL16271513 | 0.72 | PDK2 (0.47) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714659-B1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | AMERICAN DYE SOURCE INC (CA) | 2017-07-05 | — | — | EP | disclosed |
| US-9382259-B2 | Compounds with oxime ester and/or acyl groups | AMERICAN DYE SOURCE, INC. (CA) | 2016-07-05 | — | — | US | disclosed |
| US-20160016964-A1 | Compounds With Oxime Ester And/Or Acyl Groups | AMERICAN DYE SOURCE, INC. (CA) | 2016-01-21 | — | — | US | disclosed |
| US-9127017-B2 | Compounds with oxime ester and/or acyl groups | AMERICAN DYE SOURCE, INC. (CA) | 2015-09-08 | — | — | US | disclosed |
| WO-2012159213-A1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | AMERICAN DYE SOURCE, INC. (CA) | 2012-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016964-A1 | Compounds With Oxime Ester And/Or Acyl Groups | SCO2, PPOX, SQOR | TTR 2812/4885S100A4 2668/4885PTPRC 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.