Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871206 | 1.00 | HCAR2 (0.54) | HCAR2MAPTNPSR1CA12CA1 | |
| SCHEMBL21126446 | 0.87 | ATM (0.48) | HCAR2MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL10985141 | 0.83 | HCAR2 (0.57) | HCAR2MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL28831576 | 0.83 | HCAR2 (0.50) | HCAR2MAPTNPSR1CA12CA1 | |
| SCHEMBL21127859 | 0.82 | HCAR2 (0.32) | HCAR2NPSR1ATM | |
| SCHEMBL21126964 | 0.82 | ATM (0.53) | HCAR2MAPTNPSR1ALDH1A1ATM | |
| SCHEMBL22897008 | 0.81 | HCAR2 (0.52) | HCAR2MAPTNPSR1CA12CA1 | |
| SCHEMBL1478285 | 0.80 | HCAR2 (0.52) | HCAR2MAPTNPSR1CA12CA1 | |
| SCHEMBL6892352 | 0.80 | HCAR2 (0.52) | HCAR2MAPTCA12CA1CA2 | |
| SCHEMBL6891801 | 0.80 | HCAR2 (0.52) | HCAR2MAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195284-B1 | PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2017-03-22 | — | — | EP | claimed |
| CN-102099010-B | The compositions that can give | 悉尼大学 | 2016-09-14 | — | — | CN | claimed |
| CN-102099407-B | Polymer microgel beads | UNIV SYDNEY | 2014-08-27 | — | — | CN | claimed |
| EP-2245001-B1 | Method for the production of 2-fluoroacyl-3-amino-acrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-20 | — | — | EP | claimed |
| US-8288582-B2 | Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2012-10-16 | — | — | US | claimed |
| US-8258335-B2 | Process for preparing 2-dihaloacyl-3-aminoacrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2012-09-04 | — | — | US | claimed |
| CN-102099407-A | Polymer microgel beads | UNIV SYDNEY | 2011-06-15 | — | — | CN | claimed |
| CN-102099010-A | Administrable compositions | UNIV SYDNEY | 2011-06-15 | — | — | CN | claimed |
| CN-102099408-A | Polymer microgel beads and method for producing same | UNIV SYDNEY | 2011-06-15 | — | — | CN | claimed |
| EP-2245001-A1 | METHOD FOR THE PRODUCTION OF 2-FLUOROACYL-3-AMINO-ACRYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | claimed |
| US-20100274049-A1 | Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-10-28 | — | — | US | claimed |
| US-20100204483-A1 | PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-08-12 | — | — | US | claimed |
| EP-2195284-A1 | PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2010-06-16 | — | — | EP | claimed |
| WO-2009083134-A1 | METHOD FOR THE PRODUCTION OF 2-FLUOROACYL-3-AMINO-ACRYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-07-09 | — | — | WO | claimed |
| EP-2072497-A1 | Method for manufacturing 2-fluoracyl-3-amino-acrylic acid derivatives | Bayer CropScience AG (DE) | 2009-06-24 | — | — | EP | claimed |
| WO-2009043444-A1 | PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-04-09 | — | — | WO | claimed |
| EP-2042482-A1 | Method for manufacturing 2-dihalogenacyl-3-amino-acrylic acid derivatives | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | claimed |
| EP-4745141-A1 | METHOD FOR PREPARING INTERMEDIATE OF ADRENERGIC RECEPTOR AGONIST | Porton Pharma Solutions Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |
| US-4346161-A | DIFFUSION TRANSFER | EASTMAN KODAK COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| US-3957710-A | Paper coating compositions from polymers of olefinically unsaturated monomers | BASF AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204483-A1 | PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES | AADAT, DDC, IDUA | HCAR2 590/4885MAPT 3232/4885NPSR1 2213/4885 |
| US-20100274049-A1 | Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives | AADAT, AADAC, ALAD | HCAR2 264/4885MAPT 3643/4885NPSR1 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.