Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28170181 | 0.92 | TSHR (0.50) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL28038694 | 0.89 | TSHR (0.47) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL2946080 | 0.87 | TSHR (0.59) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| Bromide SCHEMBL28073958 | 0.85 | TSHR (0.57) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| Hydrochloric Acid SCHEMBL1238012 | 0.85 | MAPT (0.60) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL864444 | 0.80 | TSHR (0.34) | TSHR | |
| SCHEMBL1683535 | 0.78 | TSHR (0.34) | TSHR | |
| SCHEMBL27605752 | 0.78 | TSHR (0.34) | TSHR | |
| SCHEMBL27632852 | 0.76 | TSHR (0.32) | TSHR | |
| SCHEMBL6116476 | 0.75 | TSHR (0.41) | TSHRCHRM2CHRM4CHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026849-A2 | CURABLE HYDROPHILIC COMPOSITIONS | 3M Innovative Properties Company (US) | 2009-02-25 | — | — | EP | claimed |
| WO-2008060677-A2 | CURABLE HYDROPHILIC COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-05-22 | — | — | WO | claimed |
| US-20070275042-A1 | CURABLE HYDROPHILIC COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY | 2007-11-29 | — | — | US | claimed |
| US-7005143-B2 | Gel materials, medical articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-02-28 | — | — | US | claimed |
| EP-1494727-A1 | GEL MATERIALS, MEDICAL ARTICLES, AND METHODS | 3M Innovative Properties Company (US) | 2005-01-12 | — | — | EP | claimed |
| US-20030203011-A1 | Gel materials, medical articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2003-10-30 | — | — | US | claimed |
| WO-2003086493-A1 | GEL MATERIALS, MEDICAL ARTICLES, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-10-23 | — | — | WO | claimed |
| EP-2462956-B2 | Absorbent medical articles | 3M INNOVATIVE PROPERTIES CO (US) | 2017-03-29 | — | — | EP | disclosed |
| EP-1897566-B1 | Gel materials, medical articles, and methods | 3M INNOVATIVE PROPERTIES CO (US) | 2017-02-22 | — | — | EP | disclosed |
| EP-1572254-B1 | ABSORBENT MEDICAL ARTICLES | 3M INNOVATIVE PROPERTIES CO (US) | 2015-11-04 | — | — | EP | disclosed |
| US-8609131-B2 | Absorbent dressing comprising hydrophilic polymer prepared via Michael reaction | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-12-17 | — | — | US | disclosed |
| EP-1855730-B1 | ABSORBENT DRESSING COMPRISING HYDROPHILIC POLYMER | 3M INNOVATIVE PROPERTIES CO (US) | 2013-12-11 | — | — | EP | disclosed |
| US-8410332-B2 | Absorbent medical articles | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-02 | — | — | US | disclosed |
| WO-2005035607-A1 | REACTIVE HYDROPHILIC OLIGOMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-04-21 | — | — | WO | disclosed |
| US-20050070688-A1 | Reactive hydrophilic oligomers | 3M INNOVATIVE PROPERTIES COMPANY | 2005-03-31 | — | — | US | disclosed |
| EP-1494727-A1 | GEL MATERIALS, MEDICAL ARTICLES, AND METHODS | 3M Innovative Properties Company (US) | 2005-01-12 | — | — | EP | disclosed |
| WO-2004060413-A1 | ABSORBENT MEDICAL ARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20040133143-A1 | Absorbent medical articles | 3M INNOVATIVE PROPERTIES COMPANY | 2004-07-08 | — | — | US | disclosed |
| US-20030203011-A1 | Gel materials, medical articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2003-10-30 | — | — | US | disclosed |
| WO-2003086493-A1 | GEL MATERIALS, MEDICAL ARTICLES, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203011-A1 | Gel materials, medical articles, and methods | PTGES, PTGS2, PTGIS | CHRM1 4744/4885CHRM3 4655/4885TSHR 4841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.