SCHEMBL1406211

SCHEMBL1406211

CC(=O)C(CCC(=O)O)(CCC(=O)O)C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
SLC15A2 Q16348 1/20 0.46
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP1A2 P05177 1/20 0.43
THRB P10828 1/20 0.43
EGLN1 Q9GZT9 2/20 0.42
ALKBH5 Q6P6C2 1/20 0.42
SUCNR1 Q9BXA5 1/20 0.42
NAALAD2 Q9Y3Q0 1/20 0.41
FFAR3 O14843 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
KDM4E B2RXH2 1/20 0.39
KDM6B O15054 1/20 0.39
KDM5C P41229 1/20 0.39
PHF8 Q9UPP1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8856972 0.90 ALDH1A1 (0.45) LMNASLC15A2ALDH1A1MEN1KMT2A
SCHEMBL27614232 0.84 ALDH1A1 (0.50) LMNASLC15A2ALDH1A1MEN1KMT2A
SCHEMBL27614240 0.82 TSHR (0.39) LMNASLC15A2ALDH1A1MEN1KMT2A
SCHEMBL9814840 0.82 ALDH1A1 (0.39) LMNASLC15A2ALDH1A1MEN1KMT2A
SCHEMBL1406314 0.80 ALDH1A1 (0.50) LMNASLC15A2ALDH1A1TDP1
SCHEMBL27595522 0.79 DGAT1 (0.36) LMNASLC15A2ALDH1A1MEN1KMT2A
SCHEMBL2454546 0.79 MEN1 (0.46) LMNAALDH1A1MEN1KMT2ACYP1A2
SCHEMBL11620113 0.78 LMNA (0.46) LMNASLC15A2ALDH1A1MEN1KMT2A
SCHEMBL1406387 0.77 MEN1 (0.44) LMNASLC15A2ALDH1A1MEN1KMT2A
SCHEMBL4810549 0.77 LMNA (0.47) LMNASLC15A2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112552158-B Preparation and application of high-absorption chrome tanning auxiliary agent containing ketocarboxylic acid structure 南京工业大学 2023-05-19 CN disclosed
EP-1490412-B1 PHOTOINITIATOR, NOVEL COMPOUND, AND PHOTOCURABLE COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2011-03-09 EP disclosed
EP-1490412-B1 PHOTOINITIATOR, NOVEL COMPOUND, AND PHOTOCURABLE COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2011-03-09 EP disclosed
CN-100473667-C Photoinitiator, novel compound and photocurable composition DAINIPPON INK & CHEMICALS (JP) 2009-04-01 CN disclosed
US-7166648-B2 Photoinitiator, novel compound, and photocurable composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-7166648-B2 Photoinitiator, novel compound, and photocurable composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-7166648-B2 Photoinitiator, novel compound, and photocurable composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-20050256218-A1 Photoinitiator, novel compound, and photocurable composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-11-17 US disclosed
CN-1642992-A Photoinitiator, photocurable composition of novel compound DAINIPPON INK & CHEMICALS (JP) 2005-07-20 CN disclosed
EP-1490412-A1 PHOTOINITIATOR, NOVEL COMPOUND, AND PHOTOCURABLE COMPOSITION DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-12-29 EP disclosed
WO-2003082929-A1 PHOTOINITIATOR, NOVEL COMPOUND, AND PHOTOCURABLE COMPOSITION DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-10-09 WO disclosed
US-5252603-A Immunosuppressive analogues and derivatives of succinylacetone CETUS CORPORATION (US) 1993-10-12 US disclosed
US-5216005-A Treating autoimmune diseases, organ tissue transplants CETUS CORPORATION (US) 1993-06-01 US disclosed
US-5173482-A A dioxoalkyl phosponate or a proline-modified polyoxyethylene glycol derivative; autoimmune diseases; organ transplants; immunoassay CETUS CORPORATION (US) 1992-12-22 US disclosed
WO-1991004734-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING 4,6-TIOXOHEPTANOIC ACID OR ITS DERIVATIVES CETUS CORPORATION (US) 1991-04-18 WO disclosed
US-4895872-A TREATING HYPERACTIVE IMMUNE SYSTEMS; AUTOIMMUNE AND GRAFT/HOST DISEASES CETUS CORPORATION (US) 1990-01-23 US disclosed
WO-1990000049-A2 IMMUNOSUPPRESSIVE ANALOGUES AND DERIVATIVES OF SUCCINYLACETONE CETUS CORPORATION (US) 1990-01-11 WO disclosed