SCHEMBL1406219

SCHEMBL1406219

OC(=Cc1ccc(Cl)c(Cl)c1)[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=Cc1ccc(Cl)c(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.44
▸ NPFFR2 Q9Y5X5 2/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ PYGL P06737 7/20 0.36
▸ GRIK1 P39086 1/20 0.35
▸ GRIK2 Q13002 1/20 0.35
▸ CHAT P28329 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ G6PC1 P35575 1/20 0.34
▸ DPEP1 P16444 1/20 0.33
▸ KMO O15229 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL376418 0.89 ALDH1A1 (0.36) ALDH1A1NPFFR2KMT2ANPSR1PYGL
SCHEMBL376014 0.87 ALDH1A1 (0.37) ALDH1A1NPFFR2KMT2ANPSR1PYGL
SCHEMBL6015157 0.84 CYP3A4 (0.36) ALDH1A1KMT2ANPSR1KMO
SCHEMBL6439481 0.84 KCNA3 (0.34) KMO
SCHEMBL6015169 0.84 KMT2A (0.35) KMT2A
SCHEMBL5230461 0.84 KCNA3 (0.34) KMO
SCHEMBL5229485 0.84 TRPA1 (0.44) ALDH1A1KMT2ANPSR1TSHRDPEP1
SCHEMBL6311091 0.84 KCNA3 (0.34) KMO
SCHEMBL6209293 0.80 KMT2A (0.39) ALDH1A1KMT2ANPSR1HSD17B10
SCHEMBL20506873 0.79 GRIK1 (0.44) ALDH1A1KMT2AGRIK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1856200-B9 COADDITIVE COMPOSITIONS AND METHODS FOR APPLYING COADDITIVE COMPOSITIONS INTO NUCLEATED POLYMER COMPOUNDS MILLIKEN & CO (US) 2011-05-11 — — EP claimed
EP-1856200-B1 COADDITIVE COMPOSITIONS AND METHODS FOR APPLYING COADDITIVE COMPOSITIONS INTO NUCLEATED POLYMER COMPOUNDS MILLIKEN & CO (US) 2011-03-09 — — EP claimed
EP-1856200-A1 COADDITIVE COMPOSITIONS AND METHODS FOR APPLYING COADDITIVE COMPOSITIONS INTO NUCLEATED POLYMER COMPOUNDS Milliken&Company (US) 2007-11-21 — — EP claimed
EP-1313741-B1 FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME MILLIKEN & CO (US) 2007-05-23 — — EP claimed
WO-2006083640-A1 COADDITIVE COMPOSITIONS AND METHODS FOR APPLYING COADDITIVE COMPOSITIONS INTO NUCLEATED POLYMER COMPOUNDS MILLIKEN & COMPANY (US) 2006-08-10 — — WO claimed
US-20060173108-A1 Co-additive compositions and methods for applying co-additive compositions into nucleated polymer compounds MILLIKEN & COMPANY 2006-08-03 — — US claimed
US-6906207-B2 Polymer additive compositions and articles comprising novel fluorinated and alkylated alditol derivatives MILLIKEN & COMPANY (US) 2005-06-14 — — US claimed
US-20030181552-A1 Polymer additive compositions and articles comprising novel fluorinated and alkylated alditol derivatives ANDERSON JOHN D (US) 2003-09-25 — — US claimed
US-6582503-B2 Modifying polyolefin properties, such as polypropylene clarification and nucleation MILLIKEN & COMPANY 2003-06-24 — — US claimed
EP-1313741-A2 FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME Milliken & Company (US) 2003-05-28 — — EP claimed
WO-2002100934-A2 POLYOLEFIN ADDITIVE COMPOSITION COMPRISING 3,4-DIMETHYL DIBENZYLIDENE SORBITOL AND 3,4-DICHLORO DIBENZYLIDENE SORBITOL MILLIKEN & COMPANY (US) 2002-12-19 — — WO claimed
US-20020188044-A1 Polyolefin additive composition comprising 3,4-dimethyl dibenzylidene sorbitol and 3,4-dichloro dibenzylidene sorbitol MILLIKEN & COMPANY 2002-12-12 — — US claimed
US-20020062034-A1 Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same MILLIKEN &COMPANY 2002-05-23 — — US claimed
WO-2002020528-A2 FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME MILLIKEN & COMPANY (US) 2002-03-14 — — WO claimed
EP-0068773-B1 POLYETHYLENE COMPOSITIONS MILLIKEN RESEARCH CORPORATION (US) 1986-02-12 — — EP claimed
US-4419473-A LOW DENSITY POLYETHYLENE, DIACETAL OF SORBITOL AND AROMATIC ALDEHYDE, STABILIZER MILLIKEN RESEARCH CORPORATION (US) 1983-12-06 — — US claimed
US-4371645-A Polyolefin plastic compositions comprising meta- or papa-derivatives (choro- or bromo-) of di-benzyuidene sorbitol MILLIKEN RESEARCH CORPORATION (US) 1983-02-01 — — US claimed
EP-0068773-A1 Polyethylene compositions MILLIKEN RESEARCH CORPORATION (US) 1983-01-05 — — EP claimed
EP-3397682-B1 POLYOLEFIN COMPOSITION MILLIKEN & CO (US) 2024-03-27 — — EP disclosed
US-4371645-A Polyolefin plastic compositions comprising meta- or papa-derivatives (choro- or bromo-) of di-benzyuidene sorbitol MILLIKEN RESEARCH CORPORATION (US) 1983-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020062034-A1 Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same ALDOA, SORD, DERA ALDH1A1 110/4885NPFFR2 400/4885KMT2A 2545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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