Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 12/20 | 0.47 |
| ▸ | LONP1 | P36776 | 4/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.47 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.47 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.47 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.47 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.47 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.47 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.47 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.47 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.47 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.47 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.47 |
| ▸ | PSMB3 | P49720 | 3/20 | 0.47 |
| ▸ | PSMA6 | P60900 | 3/20 | 0.47 |
| ▸ | PSMA8 | Q8TAA3 | 3/20 | 0.47 |
| ▸ | PSMB7 | Q99436 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406198 | 0.89 | PSMB5 (0.61) | PSMB5LONP1PSMB1PSMB2PSMB11 | |
| SCHEMBL234157 | 0.84 | PSMB5 (0.54) | PSMB5LONP1PSMB1PSMB2PSMB11 | |
| SCHEMBL1406094 | 0.83 | CTSL (0.41) | PSMB5LONP1PSMB1PSMB2PSMB11 | |
| Leucine SCHEMBL3816604 | 0.75 | GPR132 (0.53) | PSMB5LONP1PSMB1PSMB2PSMB11 | |
| SCHEMBL15689578 | 0.74 | PSMB5 (0.66) | PSMB5CA1CA2CTRB1CTSL | |
| SCHEMBL6860349 | 0.74 | ECE1 (0.62) | CTSLLMNAECE1GPR132CMKLR2 | |
| Leucine SCHEMBL1406326 | 0.73 | GPR132 (0.56) | PSMB5LMNAECE1GPR132CMKLR2 | |
| SCHEMBL1406021 | 0.73 | PSMB5 (0.51) | PSMB5LONP1PSMB1PSMB2PSMB11 | |
| SCHEMBL234139 | 0.72 | PSMB5 (0.71) | PSMB5LONP1PSMB1PSMB2PSMB11 | |
| SCHEMBL3202113 | 0.71 | GPR132 (0.53) | PSMB5LMNAECE1GPR132CMKLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355910-B1 | FORMULATION OF BORONIC ACID COMPOUNDS | US OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVICES (US) | 2011-03-09 | — | — | EP | claimed |