Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20255477 | 0.74 | ESR2 (0.50) | ESR2KDM4EGLAHTTKMT2A | |
| SCHEMBL14064112 | 0.71 | ESR2 (0.47) | ESR2MAPK8MAPK10DEGS1 | |
| SCHEMBL23503919 | 0.70 | ESR2 (0.46) | ESR2KDM4EGLAHTTKMT2A | |
| SCHEMBL14423341 | 0.70 | ESR2 (0.59) | ESR2KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL20249182 | 0.70 | ESR2 (0.46) | ESR2KDM4EGLAHTTKMT2A | |
| SCHEMBL178486 | 0.70 | ESR2 (1.00) | ESR2CYP3A4CYP2C9ESR1 | |
| SCHEMBL605342 | 0.70 | ESR2 (1.00) | ESR2CYP3A4CYP2C9ESR1 | |
| SCHEMBL3736028 | 0.69 | KMT2A (0.54) | ESR2KDM4EGLAHTTKMT2A | |
| SCHEMBL30817495 | 0.68 | ESR2 (0.35) | ESR2KDM4E | |
| SCHEMBL6906434 | 0.68 | ESR2 (0.65) | ESR2KMT2ACYP3A4CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425354-B2 | Photopolymerizable liquid crystal composition, its polymer or polymer composition, and optical compensation element | CHISSO CORPORATION (JP) | 2008-09-16 | — | — | US | disclosed |