Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556733 | 0.79 | SLC2A1 (0.48) | SLC2A1PTGS2 | |
| SCHEMBL14065652 | 0.78 | SENP1 (0.36) | SLC2A1KMT2AALDH1A1POLBBRD4 | |
| SCHEMBL3396240 | 0.77 | IKBKB (0.35) | SLC2A1KMT2AALDH1A1POLBBRD4 | |
| SCHEMBL3560834 | 0.75 | SLC2A1 (0.44) | SLC2A1ALDH1A1BRD4KDM4E | |
| SCHEMBL3396786 | 0.73 | BRD4 (0.35) | SLC2A1BRD4HSD17B10 | |
| SCHEMBL14065656 | 0.72 | SLC2A1 (0.38) | SLC2A1KMT2AALDH1A1POLBBRD4 | |
| SCHEMBL9265685 | 0.70 | SLC2A1 (0.62) | SLC2A1KMT2AALDH1A1POLBBRD4 | |
| SCHEMBL9264323 | 0.69 | SLC2A1 (0.60) | SLC2A1KMT2AALDH1A1POLBBRD4 | |
| SCHEMBL3392710 | 0.68 | SLC2A1 (0.48) | SLC2A1KMT2AALDH1A1POLBBRD4 | |
| SCHEMBL9262778 | 0.68 | TYMP (0.51) | SLC2A1KMT2ATYMPMEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1967515-A1 | Heterocyclic compounds | GLAXO GROUP LIMITED (GB) | 2008-09-10 | — | — | EP | disclosed |