Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396240 | 0.87 | IKBKB (0.35) | SLC2A1MAPK1MEN1HTTKMT2A | |
| SCHEMBL3396786 | 0.83 | BRD4 (0.35) | SLC2A1BRD4HSD17B10 | |
| SCHEMBL14065459 | 0.78 | SLC2A1 (0.40) | SLC2A1CSF1RMEN1CYP2D6CYP2C9 | |
| SCHEMBL13439218 | 0.73 | TLR8 (0.42) | SLC2A1MAPTKDM4EALDH1A1 | |
| SCHEMBL3558780 | 0.73 | SCN9A (0.40) | SLC2A1 | |
| SCHEMBL13049774 | 0.70 | DGAT1 (0.40) | — | |
| SCHEMBL9264323 | 0.68 | SLC2A1 (0.60) | GAASLC2A1MAPK1MEN1MAPT | |
| SCHEMBL3556733 | 0.67 | SLC2A1 (0.48) | SLC2A1MMP2 | |
| SCHEMBL9262778 | 0.67 | TYMP (0.51) | GAASLC2A1MEN1KMT2A | |
| SCHEMBL3392595 | 0.67 | SLC2A1 (0.48) | GAASLC2A1MAPK1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1967515-A1 | Heterocyclic compounds | GLAXO GROUP LIMITED (GB) | 2008-09-10 | — | — | EP | disclosed |