Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206554 | 0.85 | TDP1 (0.61) | TDP1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL5951090 | 0.84 | KMT2A (0.53) | TDP1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL5816846 | 0.84 | LMNA (0.65) | TDP1ALDH1A1KMT2ASCN1ASCN2A | |
| SCHEMBL14947120 | 0.83 | NPC1 (0.67) | TDP1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL5950537 | 0.83 | CA1 (0.59) | RAB9ANPC1KMT2AMAPTGAA | |
| Hydrochloric Acid SCHEMBL1066508 | 0.83 | KMT2A (0.54) | TDP1RAB9ANPC1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL1066683 | 0.82 | LMNA (0.62) | TDP1ALDH1A1KMT2ASCN1ASCN2A | |
| SCHEMBL23630890 | 0.81 | RAB9A (0.61) | RAB9ANPC1ALDH1A1MAPTGAA | |
| SCHEMBL14369871 | 0.81 | TDP1 (0.55) | TDP1RAB9ANPC1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL1067309 | 0.81 | CA1 (0.58) | RAB9ANPC1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234283-A1 | Glutathione peroxidase mimetics for treatment of neurodegenerative, pulmonary and inflammatory diseases | RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES (IL) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234283-A1 | Glutathione peroxidase mimetics for treatment of neurodegenerative, pulmonary and inflammatory diseases | GPX1, GPX4, MPO | TDP1 807/4885RAB9A 3425/4885NPC1 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.