SCHEMBL14067008

SCHEMBL14067008

CN1C(=O)C2C=CC(C2)C1=O

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 1/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
MGLL Q99685 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
TSHR P16473 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CYP19A1 P11511 1/20 0.31
USP2 O75604 1/20 0.31
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13534413 0.75 ALDH1A1 (0.41) KMT2AALDH1A1KDM4ETDP1MEN1
SCHEMBL12269665 0.75 KMT2A (0.32) KMT2AGSK3AGSK3BMGLL
SCHEMBL14629445 0.73
SCHEMBL13291136 0.70 ALDH1A1 (0.61) KMT2AALDH1A1KDM4ETDP1MEN1
SCHEMBL19683939 0.70 ALDH1A1 (0.61) KMT2AALDH1A1KDM4ETDP1MEN1
SCHEMBL19683938 0.70 ALDH1A1 (0.61) KMT2AALDH1A1KDM4ETDP1MEN1
SCHEMBL12747580 0.70 ALDH1A1 (0.61) KMT2AALDH1A1KDM4ETDP1MEN1
SCHEMBL278527 0.70 ALDH1A1 (0.61) KMT2AALDH1A1KDM4ETDP1MEN1
SCHEMBL22174075 0.70 ALDH1A1 (0.61) KMT2AALDH1A1KDM4ETDP1MEN1
SCHEMBL19444546 0.70 ALDH1A1 (0.61) KMT2AALDH1A1KDM4ETDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080220597-A1 Photoresists and methods for use thereof ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2008-09-11 US disclosed
US-7297616-B2 Methods, photoresists and substrates for ion-implant lithography ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2007-11-20 US disclosed