Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19683939 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL22174075 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL12747580 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL278527 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL19444546 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL13291136 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL13534106 | 0.86 | POLB (0.52) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL13239534 | 0.86 | POLB (0.52) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL793891 | 0.86 | POLB (0.52) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL14727215 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106738-A1 | BRUSH-ARM STAR POLYMERS, CONJUGATES AND PARTICLES, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-06-14 | — | — | WO | disclosed |
| WO-2017214337-A1 | DRUG DELIVERY POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-14 | — | — | WO | disclosed |
| US-20170348431-A1 | DRUG DELIVERY POLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348431-A1 | DRUG DELIVERY POLYMERS AND USES THEREOF | BRAP, PAICS, BRPF1 | ALDH1A1 2807/4885TDP1 3223/4885MEN1 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.