SCHEMBL278527

SCHEMBL278527

CN1C(=O)C2C3C=CC(C3)C2C1=O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
TDP1 Q9NUW8 1/20 0.61
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
RAB9A P51151 2/20 0.59
KDM4E B2RXH2 1/20 0.56
TSHR P16473 3/20 0.53
HTT P42858 2/20 0.53
USP2 O75604 2/20 0.53
HSD17B10 Q99714 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.52
LMNA P02545 1/20 0.52
RECQL P46063 1/20 0.52
MAPK1 P28482 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.50
CYP3A4 P08684 1/20 0.49
CYP2C19 P33261 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19683939 1.00 ALDH1A1 (0.61) ALDH1A1TDP1MEN1KMT2ARAB9A
SCHEMBL22174075 1.00 ALDH1A1 (0.61) ALDH1A1TDP1MEN1KMT2ARAB9A
SCHEMBL19683938 1.00 ALDH1A1 (0.61) ALDH1A1TDP1MEN1KMT2ARAB9A
SCHEMBL12747580 1.00 ALDH1A1 (0.61) ALDH1A1TDP1MEN1KMT2ARAB9A
SCHEMBL19444546 1.00 ALDH1A1 (0.61) ALDH1A1TDP1MEN1KMT2ARAB9A
SCHEMBL13291136 1.00 ALDH1A1 (0.61) ALDH1A1TDP1MEN1KMT2ARAB9A
SCHEMBL13534106 0.86 POLB (0.52) ALDH1A1TDP1MEN1KMT2ARAB9A
SCHEMBL13239534 0.86 POLB (0.52) ALDH1A1TDP1MEN1KMT2ARAB9A
SCHEMBL793891 0.86 POLB (0.52) ALDH1A1TDP1MEN1KMT2ARAB9A
SCHEMBL14727215 0.86 ALDH1A1 (0.52) ALDH1A1TDP1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4080491-A CATALYST CONTAINS ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF TUNGSTEN OR MOLYBDENUM OXIDE AND A PHOSPHOROUS HALIDE OR OXYHALIDE SHOWA DENKO K.K. (JA) 1978-03-21 US claimed
JP-54076700-A None JP disclosed
US-12589157-B1 Compositions of drug delivery agents and methods of use thereof WASHINGTON UNIVERSITY (US) 2026-03-31 US disclosed
US-12377407-B2 Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-08-05 US disclosed
US-12037319-B2 Curable compound DAICEL CORPORATION (JP) 2024-07-16 US disclosed
US-12037319-B2 Curable compound DAICEL CORPORATION (JP) 2024-07-16 US disclosed
US-20240210827-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-27 US disclosed
US-20240210827-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-27 US disclosed
WO-2024130537-A1 ELECTROLYTE, ELECTROCHEMICAL APPARATUS AND ELECTRONIC APPARATUS 东莞新能源科技有限公司 2024-06-27 WO disclosed
WO-2024130535-A1 ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE 东莞新能源科技有限公司 2024-06-27 WO disclosed
US-4105608-A HIGH IMPACT COMPOSITION OF RING-OPENING POLYMERIZATION PRODUCT SHOWA DENKO K.K. (JP) 1978-08-08 US disclosed
US-4104325-A Resin composition comprising cyano-substituted norborene polymers blended with graft copolymers SHOWA DENKO K.K. (JP) 1978-08-01 US disclosed
US-4080491-A CATALYST CONTAINS ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF TUNGSTEN OR MOLYBDENUM OXIDE AND A PHOSPHOROUS HALIDE OR OXYHALIDE SHOWA DENKO K.K. (JA) 1978-03-21 US disclosed
US-4068063-A Catalyst composition for ring-opening polymerization of norbornene derivatives and process for polymerizing same JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1978-01-10 US disclosed
US-4059561-A AND A HALOGEN COMPOUND SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-11-22 US disclosed
US-4028482-A LOW VISCOSITY POLYALKENAMER SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-06-07 US disclosed
US-4022954-A ADHESIVES, FLOCCULATING AGENTS, ION EXCHANGE RESINS, MOLDING AGENTS SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-05-10 US disclosed
US-4021510-A HIGH IMPACT STRENGTH SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-05-03 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed
US-3959234-A CATALYSTS OF ORGANOALUMINUM COMPOUNDS AND A TUNGSTEN OR MOLYBDENUM COMPOUND, RING-OPENING SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589157-B1 Compositions of drug delivery agents and methods of use thereof CALR, ABCC1, CALU ALDH1A1 3670/4885TDP1 4120/4885MEN1 3501/4885
US-12377407-B2 Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis PPOX, CYBA, CYBB ALDH1A1 1395/4885TDP1 2445/4885MEN1 1935/4885
US-12037319-B2 Curable compound CCT5, PGA5, KDM5B ALDH1A1 3558/4885TDP1 1585/4885MEN1 2220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.