Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27098482 | 0.81 | HTR3E (0.50) | SLC6A2SLC6A3ALDH1A1CHRM3CHRM2 | |
| SCHEMBL14068922 | 0.81 | LMNA (0.48) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL9127307 | 0.81 | SLC6A2 (0.44) | SLC6A2SLC6A3LMNACYP1A2CYP2D6 | |
| SCHEMBL14068930 | 0.78 | LMNA (0.39) | SLC6A2SLC6A3LMNACYP1A2CYP2D6 | |
| SCHEMBL14068924 | 0.77 | SLC6A2 (0.40) | SLC6A2SLC6A3LMNACYP1A2CYP2D6 | |
| SCHEMBL14068925 | 0.77 | CYP2C19 (0.41) | SLC6A2SLC6A3LMNACYP1A2CYP2D6 | |
| SCHEMBL27755191 | 0.77 | ALDH1A1 (0.48) | SLC6A2SLC6A3LMNACYP1A2CYP2D6 | |
| SCHEMBL14068901 | 0.76 | KMT2A (0.44) | SLC6A2SLC6A3LMNACYP1A2CYP2D6 | |
| SCHEMBL11134603 | 0.76 | CYP2C19 (0.41) | SLC6A2SLC6A3LMNACYP1A2CYP2D6 | |
| SCHEMBL4978863 | 0.76 | SMN1; SMN2 (0.46) | SLC6A3HTR2AHRH1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234498-A1 | Pyrovalerone Analogues and Therapeutic Uses Thereof | PRESIDENT AND FELLOW OF HARVARD COLLEGE (US) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234498-A1 | Pyrovalerone Analogues and Therapeutic Uses Thereof | SLC6A2, SLC6A4, SLC6A3 | SLC6A2 1/4885SLC6A3 3/4885LMNA 4124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.