Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MITF | O75030 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29380532 | 0.97 | ALDH1A1 (0.61) | ALDH1A1RAB9AMITFSMN1; SMN2HTT | |
| SCHEMBL18897724 | 0.85 | SLC6A4 (0.77) | ALDH1A1RAB9AMITFSMN1; SMN2HTT | |
| SCHEMBL7718161 | 0.84 | ALDH1A1 (0.60) | ALDH1A1RAB9AMITFSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL29766065 | 0.84 | SLC6A4 (0.75) | ALDH1A1RAB9AMITFSMN1; SMN2HTT | |
| SCHEMBL6862148 | 0.83 | ALDH1A1 (0.58) | ALDH1A1RAB9AMITFSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL9850462 | 0.82 | HRH3 (0.71) | ALDH1A1RAB9AMITFSMN1; SMN2HTT | |
| SCHEMBL7713720 | 0.81 | SLC6A4 (0.53) | ALDH1A1RAB9AMITFSMN1; SMN2HTT | |
| SCHEMBL9170851 | 0.81 | ALDH1A1 (0.73) | ALDH1A1RAB9AMITFSMN1; SMN2HTT | |
| SCHEMBL7718745 | 0.81 | ALDH1A1 (0.60) | ALDH1A1RAB9AMITFSMN1; SMN2HTT | |
| SCHEMBL7719239 | 0.81 | ALDH1A1 (0.59) | ALDH1A1RAB9AMITFSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234498-A1 | Pyrovalerone Analogues and Therapeutic Uses Thereof | PRESIDENT AND FELLOW OF HARVARD COLLEGE (US) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234498-A1 | Pyrovalerone Analogues and Therapeutic Uses Thereof | SLC6A2, SLC6A4, SLC6A3 | ALDH1A1 1868/4885RAB9A 1515/4885MITF 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.