Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.69 |
| ▸ | DRD3 | P35462 | 2/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29766065 | 0.99 | SLC6A4 (0.75) | SLC6A4CHRM2ADRA2BDRD3SIGMAR1 | |
| SCHEMBL4936687 | 0.87 | SLC6A4 (1.00) | SLC6A4CHRM2ADRA2BDRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9850462 | 0.86 | HRH3 (0.71) | SLC6A4CHRM2ADRA2BDRD3SIGMAR1 | |
| SCHEMBL6862360 | 0.86 | SLC6A4 (0.69) | SLC6A4CHRM2ADRA2BDRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL29380532 | 0.85 | ALDH1A1 (0.61) | SLC6A4CHRM2ADRA2BDRD3SIGMAR1 | |
| SCHEMBL14068950 | 0.85 | ALDH1A1 (0.60) | SLC6A4CHRM2ADRA2BDRD3SIGMAR1 | |
| Tolperisone SCHEMBL4516510 | 0.82 | CHRM2 (1.00) | SLC6A4CHRM2ADRA2BDRD3SIGMAR1 | |
| Tolperisone SCHEMBL148499 | 0.82 | CHRM2 (1.00) | SLC6A4CHRM2ADRA2BDRD3SIGMAR1 | |
| SCHEMBL21451092 | 0.82 | CHRM2 (1.00) | SLC6A4CHRM2ADRA2BDRD3SIGMAR1 | |
| Tolperisone SCHEMBL17223884 | 0.82 | CHRM2 (1.00) | SLC6A4CHRM2ADRA2BDRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200390754-A1 | METHODS OF ADMINISTERING TOLPERISONE | NEURANA PHARMACEUTICALS, INC. | 2020-12-17 | — | — | US | disclosed |
| US-9662317-B2 | Methods of administering tolperisone for therapeutic purposes | SANOCHEMIA PHARMAZEUTIKA AG (AT) | 2017-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390754-A1 | METHODS OF ADMINISTERING TOLPERISONE | ACHE, THOP1, CHAT | SLC6A4 20/4885CHRM2 107/4885ADRA2B 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.