SCHEMBL14070944

SCHEMBL14070944

Fc1cccc2c1OC(CCC1CCCCC1)CC2

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 3/20 0.34
BCHE P06276 1/20 0.33
NFKB1 P19838 4/20 0.33
NFKB2 Q00653 4/20 0.33
RELA Q04206 4/20 0.33
DRD2 P14416 2/20 0.32
DRD3 P35462 2/20 0.32
PRKAB2 O43741 1/20 0.32
PRKAG1 P54619 1/20 0.32
PRKAA2 P54646 1/20 0.32
PRKAA1 Q13131 1/20 0.32
PRKAG3 Q9UGI9 1/20 0.32
PRKAG2 Q9UGJ0 1/20 0.32
PRKAB1 Q9Y478 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14070942 0.84 FFAR4 (0.33) BCHENFKB1NFKB2RELA
SCHEMBL14070980 0.78 FFAR4 (0.31) NFKB1NFKB2RELA
SCHEMBL7394577 0.77 PRKAB2 (0.46) NFKB1NFKB2RELADRD2DRD3
SCHEMBL14070952 0.77 SIGMAR1 (0.35) BCHENFKB1NFKB2RELA
SCHEMBL14070931 0.75 STS (0.39) DRD2DRD3
SCHEMBL14070941 0.73 DRD2 (0.36) OPRL1DRD2DRD3
SCHEMBL14070956 0.72 STS (0.38) DRD2DRD3
SCHEMBL14071036 0.70 FFAR4 (0.30)
SCHEMBL3349343 0.70 HPGD (0.38) DRD2DRD3
SCHEMBL4794533 0.69 NFKB1 (0.41) NFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7429411-B2 Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition CHISSO PETROCHEMICAL CORPORATION (JP) 2008-09-30 US disclosed
US-7429411-B2 Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition CHISSO PETROCHEMICAL CORPORATION (JP) 2008-09-30 US disclosed