Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 13/20 | 0.41 |
| ▸ | ATF1 | P18846 | 12/20 | 0.41 |
| ▸ | XPO1 | O14980 | 4/20 | 0.40 |
| ▸ | JUN | P05412 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539891 | 0.81 | NFKB1 (0.55) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL79014 | 0.81 | NFKB1 (0.60) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL3066551 | 0.79 | KDM4E (0.46) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL3441123 | 0.77 | NFKB1 (0.40) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL29913514 | 0.76 | — | — | |
| SCHEMBL28480540 | 0.76 | — | — | |
| SCHEMBL8540300 | 0.76 | KDM4E (0.40) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL3060847 | 0.74 | NFKB1 (0.38) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL1550532 | 0.68 | ADORA3 (0.42) | KDM4E | |
| SCHEMBL30328567 | 0.68 | MBOAT4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |