Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14078569 | 0.91 | MGLL (0.47) | MGLLMEN1KMT2A | |
| SCHEMBL14078567 | 0.82 | MGLL (0.47) | MGLLMEN1KMT2A | |
| SCHEMBL14469477 | 0.73 | KMT2A (0.58) | MEN1KMT2A | |
| SCHEMBL14469569 | 0.73 | ALDH1A1 (0.47) | MEN1KMT2A | |
| SCHEMBL14469179 | 0.73 | ADRB2 (0.54) | MAPTMEN1KMT2A | |
| SCHEMBL14469562 | 0.73 | L3MBTL1 (0.47) | MAPTMEN1KMT2A | |
| SCHEMBL14469190 | 0.73 | CYP3A4 (0.48) | MEN1KMT2A | |
| SCHEMBL14469285 | 0.72 | L3MBTL1 (0.44) | MAPTMEN1KMT2A | |
| SCHEMBL14469549 | 0.72 | KDM4E (0.50) | MAPTMEN1KMT2A | |
| SCHEMBL14469478 | 0.72 | SMN1; SMN2 (0.43) | MAPTDRD2DRD4DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008108957-A2 | PIPERIDINYL-PIPERIDINE AND PIPERAZINYL-PIPERIDINE FOR USE IN THE TREATMENT OF DIABETES OR PAIN | SCHERING CORPORATION (US) | 2008-09-12 | — | — | WO | disclosed |