SCHEMBL14080397

SCHEMBL14080397

FC(F)CN(Cc1ccc(Cl)nc1)c1ccoc1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CHRNA1 P02708 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29576693 0.83 ESR1 (0.34) GAAMAPTKDM4EL3MBTL1ALDH1A1
SCHEMBL29576826 0.81 GAA (0.32) GAAMAPTKDM4EL3MBTL1CHRNA1
SCHEMBL29577987 0.81 MDM2 (0.31) GAAMAPT
SCHEMBL29576972 0.81 GBA1 (0.36) GAAMAPTKDM4EL3MBTL1
SCHEMBL29577153 0.80 CTSL (0.35) GAAMAPTKDM4EL3MBTL1
SCHEMBL29577376 0.80 GAA (0.32) GAAMAPTKDM4EL3MBTL1
SCHEMBL29578315 0.80 PDE2A (0.38) GAAMAPTALDH1A1
SCHEMBL29576840 0.80 GBA1 (0.39) GAAMAPTKDM4EL3MBTL1
SCHEMBL29576922 0.79 CTSL (0.34) GAAMAPTKDM4EL3MBTL1
SCHEMBL29576842 0.79 KCNQ3 (0.34) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119453212-A Insecticidal composition and application thereof 江苏明德立达作物科技有限公司 2025-02-18 CN disclosed
WO-2022168993-A1 METHODS FOR SUPPRESSING SOIL PESTS MITSUI CHEMICALS AGRO, INC. (JP) 2022-08-11 WO disclosed
EP-2582242-B1 COMBINATIONS OF ACTIVE SUBSTANCES WITH INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER IP GMBH (DE) 2016-12-28 EP disclosed
EP-2580335-A1 METHODS AND MEANS TO MODIFY A PLANT GENOME AT A NUCLEOTIDE SEQUENCE COMMONLY USED IN PLANT GENOME ENGINEERING Bayer CropScience NV (BE) 2013-04-17 EP disclosed
US-8324392-B2 Solid form of 4-[[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl)amino]furan-2(5H)-one BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed