Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003275 | 0.83 | CYP3A4 (0.38) | CA12CA9ADRB2KMT2AMTNR1A | |
| SCHEMBL25004073 | 0.79 | TYMS (0.43) | ADRB2KMT2AGAANPSR1 | |
| SCHEMBL6683869 | 0.76 | HTR6 (0.47) | ADRB2MTNR1AMTNR1BGAAHTR6 | |
| SCHEMBL14083903 | 0.72 | NPSR1 (0.32) | CA12CA9KMT2ANPSR1 | |
| SCHEMBL7391653 | 0.68 | KEAP1 (0.43) | CA12CA9KMT2A | |
| SCHEMBL16247863 | 0.67 | CA12 (0.42) | CA12CA9KMT2AALOX12 | |
| SCHEMBL24202154 | 0.67 | CA12 (0.38) | CA12CA9ADRB2KMT2AHTR6 | |
| SCHEMBL7385627 | 0.66 | EGFR (0.35) | CA12CA9KMT2AMTNR1AMTNR1B | |
| Fluorene SCHEMBL27608186 | 0.65 | MAOA (0.48) | MTNR1AMTNR1BHTR1AHTR2AHTR2C | |
| SCHEMBL6173202 | 0.63 | CA12 (0.42) | CA12CA9KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106204-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X-PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |