Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CASP9 | P55211 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952805 | 1.00 | CA12 (0.42) | CA12CA9PARP1PDPK1PARP10 | |
| SCHEMBL2863342 | 0.71 | HTR6 (0.42) | CA12CA9PARP1PDPK1PARP10 | |
| SCHEMBL16247863 | 0.69 | CA12 (0.42) | CA12CA9PARP1PDPK1PARP10 | |
| SCHEMBL2675467 | 0.68 | CA12 (0.41) | CA12CA9PARP1MAOACES1 | |
| SCHEMBL28793775 | 0.67 | CA12 (0.40) | CA12CA9PARP1PDPK1PARP10 | |
| SCHEMBL14940557 | 0.67 | CA12 (0.40) | CA12CA9PARP1KDM4EALDH1A1 | |
| SCHEMBL28300619 | 0.67 | CA12 (0.40) | CA12CA9PARP1PDPK1PARP10 | |
| SCHEMBL7749803 | 0.67 | CES1 (0.43) | PARP1PDPK1PARP10PARP11MAOA | |
| SCHEMBL11841854 | 0.67 | MAOA (0.48) | METAP2MAOACES1TDP2CASP3 | |
| SCHEMBL29648452 | 0.67 | CES1 (0.43) | PARP1PDPK1PARP10PARP11MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165591-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | IMMUTHER PHARMATECH (SHANGHAI) CO., LTD. (CN) | 2023-09-07 | — | — | WO | disclosed |
| CN-102445845-A | Colored composition for color filter, color filter and method of producing the same, liquid crystal display device, organic electro-luminescence display device, and solid-state imaging element | FUJIFILM CORP | 2012-05-09 | — | — | CN | disclosed |
| CN-101124516-B | Pattern forming material, pattern forming apparatus, and pattern forming method | FUJI PHOTO FILM CO LTD | 2012-01-18 | — | — | CN | disclosed |
| EP-1140904-B1 | FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORP (US) | 2005-04-20 | — | — | EP | disclosed |
| US-6800636-B2 | FOR THERAPY OF CANCER | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |
| US-20030040520-A1 | Farnesyl protein transferase inhibitors | GUZI TIMOTHY (US) | 2003-02-27 | — | — | US | disclosed |
| US-6362188-B1 | ANTICANCER AGENTS | SCHERING CORPORATION | 2002-03-26 | — | — | US | disclosed |
| EP-1140904-A1 | FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037458-A1 | FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 2000-06-29 | — | — | WO | disclosed |
| WO-1999032485-A1 | 3-OXAZOL-5-YL-1-OXO-1,2-DIHYDROISOQUINOLINE-4-PROPANAMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION | SANOFI-SYNTHELABO (FR) | 1999-07-01 | — | — | WO | disclosed |
| CN-1131150-A | 3-phenyl isoquinolin-1(2H)-one derivant, its preparation method and medicinal use thereof | SYNTHELABO (FR) | 1996-09-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040520-A1 | Farnesyl protein transferase inhibitors | FNTA, FNTB, CETP | CA12 4355/4885CA9 2312/4885PARP1 4251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.