Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15098354 | 0.84 | MAP3K12 (0.43) | GNRHRKCNH2SIGMAR1GRIN2B | |
| SCHEMBL12126202 | 0.83 | MAP3K12 (0.42) | GNRHRKCNH2SIGMAR1GRIN2BTDP1 | |
| SCHEMBL12126259 | 0.83 | ALDH1A1 (0.42) | LMNAGNRHRKCNH2GRIN2B | |
| SCHEMBL12126240 | 0.80 | CYP2A13 (0.42) | GNRHRKCNH2CXCR4GRIN2BMEN1 | |
| SCHEMBL15266356 | 0.80 | LMNA (0.39) | LMNASIGMAR1CXCR4MEN1CHRM2 | |
| SCHEMBL12424285 | 0.79 | ACHE (0.44) | GNRHRKCNH2MEN1KMT2AHRH3 | |
| SCHEMBL27325094 | 0.78 | MPO (0.40) | LMNASIGMAR1CXCR4APOBEC3ACTDSP1 | |
| SCHEMBL27324060 | 0.78 | LMNA (0.38) | LMNASIGMAR1CXCR4APOBEC3ACTDSP1 | |
| SCHEMBL12384830 | 0.75 | TLR9 (0.40) | GNRHRKCNH2GRIN2B | |
| SCHEMBL15297034 | 0.73 | KCNH2 (0.43) | GNRHRKCNH2GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115381-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2008-09-25 | — | — | WO | disclosed |