Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080220 | 0.94 | ADRB2 (0.44) | ADRB2SIGMAR1CYP3A4IDO1MIF | |
| SCHEMBL21084402 | 0.89 | ADRB2 (0.48) | ADRB2PDPK1HTR3AMIF | |
| SCHEMBL16674489 | 0.83 | ADRB2 (0.49) | ADRB2PDPK1CYP3A4MIF | |
| SCHEMBL13608769 | 0.82 | ADRB2 (0.47) | ADRB2PDPK1IDO1 | |
| SCHEMBL25232794 | 0.80 | HTR3E (0.48) | ADRB2IDO1HTR3AMIF | |
| SCHEMBL14356992 | 0.80 | TAAR1 (0.43) | ADRB2PDPK1IDO1 | |
| SCHEMBL14937214 | 0.80 | ESR1 (0.50) | ADRB2CYP3A4HTR3AMIF | |
| SCHEMBL16212624 | 0.80 | TAAR1 (0.43) | ADRB2PDPK1SIGMAR1IDO1HTR3A | |
| SCHEMBL16212606 | 0.80 | MAOB (0.50) | ADRB2PDPK1SIGMAR1CYP3A4HTR3A | |
| SCHEMBL13526333 | 0.79 | HTR3A (0.53) | SIGMAR1IDO1HTR3AMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106204-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X-PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |