Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21084402 | 0.89 | ADRB2 (0.48) | ADRB2MAOBPDPK1 | |
| SCHEMBL14270135 | 0.88 | TAAR1 (0.46) | TAAR1C3AR1MAOBAOC3IDO1 | |
| SCHEMBL16674489 | 0.83 | ADRB2 (0.49) | ADRB2MAOBPDPK1 | |
| SCHEMBL13608769 | 0.82 | ADRB2 (0.47) | TAAR1ADRB2C3AR1PDPK1IDO1 | |
| SCHEMBL25232794 | 0.80 | HTR3E (0.48) | TAAR1ADRB2C3AR1MAOBAOC3 | |
| SCHEMBL16212624 | 0.80 | TAAR1 (0.43) | TAAR1ADRB2PDPK1IDO1 | |
| SCHEMBL14080940 | 0.80 | ADRB2 (0.43) | ADRB2PDPK1IDO1 | |
| SCHEMBL14937214 | 0.80 | ESR1 (0.50) | TAAR1ADRB2 | |
| SCHEMBL16212606 | 0.80 | MAOB (0.50) | ADRB2MAOBCYP19A1PDPK1LOXL2 | |
| SCHEMBL13526333 | 0.79 | HTR3A (0.53) | MAOBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018165520-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VPS-3, INC. (US) | 2018-09-13 | — | — | WO | disclosed |
| US-7291744-B2 | N-ureidoalkyl-amino compounds as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291744-B2 | N-ureidoalkyl-amino compounds as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-06 | — | — | US | disclosed |