Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922686 | 0.83 | TTR (0.42) | ADRA2AMAPK1TAAR1ADRA1AKDM4E | |
| SCHEMBL14899803 | 0.82 | ADRA2A (0.42) | ABATENPP2HDAC1ADRA2AMAPK1 | |
| SCHEMBL11947298 | 0.82 | ABAT (0.41) | ABATENPP2HDAC1ADRA2AMAPK1 | |
| SCHEMBL28046511 | 0.75 | HRH3 (0.36) | ABATENPP2TAAR1MAPTGAA | |
| SCHEMBL27717593 | 0.75 | ALDH1A1 (0.47) | TAAR1MAPTALDH1A1LOXL2 | |
| SCHEMBL110644 | 0.75 | KDM4E (0.67) | ABATADRA2AMAPK1TAAR1ADRA1A | |
| SCHEMBL29359577 | 0.75 | KDM4E (0.67) | ABATADRA2AMAPK1TAAR1ADRA1A | |
| SCHEMBL6012110 | 0.73 | MAOB (0.43) | MAPK1KDM4EMAPTRECQLALDH1A1 | |
| Bromide SCHEMBL20553882 | 0.73 | KDM4E (0.64) | ABATADRA2AMAPK1TAAR1ADRA1A | |
| Hydrochloric Acid SCHEMBL30964291 | 0.73 | KDM4E (0.68) | ABATADRA2AMAPK1TAAR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115381-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2008-09-25 | — | — | WO | disclosed |