Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14081606 | 0.82 | ABAT (0.43) | ABATENPP2HDAC1ADRA2AMAPK1 | |
| SCHEMBL14899803 | 0.80 | ADRA2A (0.42) | ABATENPP2HDAC1ADRA2AMAPK1 | |
| SCHEMBL29359577 | 0.73 | KDM4E (0.67) | ABATADRA2AMAPK1ADRA1AKDM4E | |
| SCHEMBL110644 | 0.73 | KDM4E (0.67) | ABATADRA2AMAPK1ADRA1AKDM4E | |
| SCHEMBL7943754 | 0.72 | ABAT (0.46) | ABATENPP2ADRA2AMAPK1ADRA1A | |
| Hydrochloric Acid SCHEMBL30964291 | 0.72 | KDM4E (0.68) | ABATADRA2AMAPK1ADRA1AKDM4E | |
| Bromide SCHEMBL20553882 | 0.72 | KDM4E (0.64) | ABATADRA2AMAPK1ADRA1AKDM4E | |
| Bromide SCHEMBL210866 | 0.72 | KDM4E (0.64) | ABATADRA2AMAPK1ADRA1AKDM4E | |
| Hydrochloric Acid SCHEMBL5071235 | 0.72 | KDM4E (0.68) | ABATADRA2AMAPK1ADRA1AKDM4E | |
| SCHEMBL14907833 | 0.71 | HDAC1 (0.46) | HDAC1MAPTGAAKLKB1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479168-A1 | 6-Substituted 2,3,4,5-Tetrahydro-1H-Benzo [d]Azepines as 5-HT2C Receptor Agonists | ELI LILLY AND COMPANY (US) | 2012-07-25 | — | — | EP | disclosed |