Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14082193 | 0.86 | PHGDH (0.62) | HCAR3NPC1RAB9AALDH1A1HTT | |
| SCHEMBL14082360 | 0.85 | NPC1 (0.51) | HCAR3KCNMA1NPC1MAPK1RAB9A | |
| SCHEMBL30739620 | 0.85 | HCAR3 (0.72) | HCAR3KCNMA1NPC1MAPK1RAB9A | |
| SCHEMBL14082647 | 0.83 | MAPT (0.50) | HCAR3KCNMA1NPC1MAPK1RAB9A | |
| SCHEMBL14083521 | 0.82 | TRPV1 (0.53) | HCAR3KCNMA1NPC1MAPK1RAB9A | |
| SCHEMBL14082518 | 0.80 | ABCB1 (0.62) | HCAR3KCNMA1NPC1ALDH1A1ABCB1 | |
| SCHEMBL14082891 | 0.77 | ABCB1 (0.61) | HCAR3KCNMA1NPC1MAPK1RAB9A | |
| SCHEMBL14082181 | 0.76 | TRPV1 (0.76) | NPC1RAB9ATRPV1 | |
| SCHEMBL6709928 | 0.75 | KCNMA1 (0.54) | HCAR3KCNMA1NPC1RAB9AALDH1A1 | |
| SCHEMBL20241807 | 0.75 | HCAR3 (0.60) | HCAR3KCNMA1NPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200524-A1 | Amide compounds as ion channel ligands and uses thereof | KELLY MICHAEL G | 2008-08-21 | — | — | US | disclosed |
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200524-A1 | Amide compounds as ion channel ligands and uses thereof | TRPV1, TRPA1, TRPV2 | HCAR3 204/4885KCNMA1 97/4885NPC1 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.