Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.64 |
| ▸ | KDM1A | O60341 | 9/20 | 0.64 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | EIF4E | P06730 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14082650 | 0.86 | MLYCD (0.67) | HDAC1KDM1AMLYCDMEN1PLA2G1B | |
| SCHEMBL14082625 | 0.84 | HDAC1 (0.69) | HDAC1KDM1AMLYCDHDAC6HDAC4 | |
| SCHEMBL14082607 | 0.84 | HDAC1 (0.72) | HDAC1KDM1AMLYCDHDAC8HDAC6 | |
| SCHEMBL14082732 | 0.84 | HDAC1 (0.66) | HDAC1KDM1AHDAC8HDAC6HDAC5 | |
| SCHEMBL14082403 | 0.84 | HDAC1 (0.61) | HDAC1KDM1AWDR5HDAC8HDAC6 | |
| SCHEMBL14082685 | 0.83 | HDAC1 (0.61) | HDAC1KDM1AMLYCDMEN1PLA2G1B | |
| SCHEMBL14082684 | 0.82 | HDAC1 (0.63) | HDAC1KDM1AHDAC8HDAC6HDAC5 | |
| SCHEMBL14082601 | 0.82 | HDAC1 (0.66) | HDAC1KDM1AHDAC8HDAC6HDAC5 | |
| SCHEMBL14082644 | 0.82 | KDM1A (0.60) | HDAC1KDM1AMEN1KMT2ATDP1 | |
| SCHEMBL14082243 | 0.81 | TAOK1 (0.62) | HDAC1KDM1AWDR5HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200524-A1 | Amide compounds as ion channel ligands and uses thereof | KELLY MICHAEL G | 2008-08-21 | — | — | US | disclosed |
| US-20080200524-A1 | Amide compounds as ion channel ligands and uses thereof | KELLY MICHAEL G | 2008-08-21 | — | — | US | disclosed |
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200524-A1 | Amide compounds as ion channel ligands and uses thereof | TRPV1, TRPA1, TRPV2 | HDAC1 556/4885KDM1A 4497/4885WDR5 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.