Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763075 | 0.74 | ESR1 (0.36) | ALDH1A1TSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL1408791 | 0.74 | ALDH1A1 (0.39) | MAPTALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL17988784 | 0.73 | MEN1 (0.38) | MAPTALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL12776571 | 0.73 | CYP2A6 (0.42) | MAPTALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL1408982 | 0.71 | KDM4E (0.45) | MAPTALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL2460600 | 0.70 | ALDH1A1 (0.37) | MAPTALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL2763850 | 0.70 | ALDH1A1 (0.35) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL12776616 | 0.70 | KDM4E (0.39) | MAPTALDH1A1KMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL4822367 | 0.70 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2AMEN1HRH4 | |
| SCHEMBL4822359 | 0.68 | SLC6A2 (0.32) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034221-B1 | DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS | LIFE TECHNOLOGIES CORP (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-2295503-A1 | Dibenzorhodamine dyes useful as fluorescent labelling agents | Applera Corporation (US) | 2011-03-16 | — | — | EP | disclosed |
| EP-2221347-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-2186801-A2 | Intermediates for synthesizing dibenzorhodamine dyes | Applera Corporation (US) | 2010-05-19 | — | — | EP | disclosed |
| EP-2179996-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-04-28 | — | — | EP | disclosed |
| US-7018431-B2 | Sulfonated diarylrhodamine dyes | APPLERA CORPORATION (US) | 2006-03-28 | — | — | US | disclosed |
| US-20040096397-A1 | Sulfonated diarylrhodamine dyes | APPLERA CORPORATION (US) | 2004-05-20 | — | — | US | disclosed |
| EP-1408090-A1 | Dibenzorhodamine dyes useful as fluorescent labelling agents | Applera Corporation (US) | 2004-04-14 | — | — | EP | disclosed |
| EP-1339798-A2 | SULFONATED DIARYLRHODAMINE DYES | Applera Corporation (US) | 2003-09-03 | — | — | EP | disclosed |
| US-6583168-B1 | Fluorescent labels of nucleosides, nucleotides, polynucleotides, and polypeptides in nucleic acid analysis | APPLERA CORPORATION | 2003-06-24 | — | — | US | disclosed |
| WO-2002044416-A2 | SULFONATED DIARYLRHODAMINE DYES AS FLUORESCENT LABELS | APPLERA CORPORATION (US) | 2002-06-06 | — | — | WO | disclosed |
| EP-1034221-A1 | DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS | THE PERKIN-ELMER CORPORATION (US) | 2000-09-13 | — | — | EP | disclosed |
| US-6051719-A | FLUORESCENT LABELING REAGENTS | THE PERKIN-ELMER CORPORATION (US) | 2000-04-18 | — | — | US | disclosed |
| WO-1999027020-A1 | DIBENZORHODAMINE DYES USEFUL AS FLOURESCENT LABELLING AGENTS | THE PERKIN-ELMER CORPORATION (US) | 1999-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040096397-A1 | Sulfonated diarylrhodamine dyes | POLL, DUT, DPYD | MAPT 4807/4885ALDH1A1 2097/4885CYP2A6 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.