Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17399699 | 0.93 | NPSR1 (0.39) | ELANELMNAMAPTNPSR1RORC | |
| SCHEMBL25011409 | 0.91 | CYP2C19 (0.42) | ELANELMNAMAPTNPSR1RORC | |
| SCHEMBL12009253 | 0.89 | NPC1 (0.38) | ELANEMAPTNPSR1RORCSMN1; SMN2 | |
| SCHEMBL14509286 | 0.87 | RORC (0.37) | ELANELMNAMAPTNPSR1RORC | |
| SCHEMBL14515734 | 0.87 | ELANE (0.33) | ELANELMNAMAPTNPSR1RORC | |
| SCHEMBL6864370 | 0.87 | ELANE (0.33) | ELANELMNAMAPTNPSR1RORC | |
| SCHEMBL13382474 | 0.86 | PGK1 (0.41) | ELANENPSR1RORCSMN1; SMN2CES2 | |
| SCHEMBL10127493 | 0.84 | ALDH1A1 (0.40) | LMNAMAPTNPSR1RORCSMN1; SMN2 | |
| SCHEMBL14515733 | 0.81 | RORC (0.34) | LMNARORCSMN1; SMN2 | |
| SCHEMBL26532178 | 0.77 | PGK1 (0.36) | ELANENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080187859-A1 | Radiation-Sensitive Resin Composition | JSR CORPORATION (JP) | 2008-08-07 | — | — | US | disclosed |
| US-20070269735-A1 | Radiation-Sensitive Resin Composition | JSR CORPORATION (JP) | 2007-11-22 | — | — | US | disclosed |
| US-7297461-B2 | Radiation sensitive resin composition | JSR CORPORATION (JP) | 2007-11-20 | — | — | US | disclosed |