Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861369 | 0.89 | SMN1; SMN2 (0.50) | ALDH1A1MEN1KMT2ANOTUMTSHR | |
| SCHEMBL4685687 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL9132803 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL28246338 | 0.78 | NOTUM (0.46) | ALDH1A1MEN1KMT2ANOTUMTSHR | |
| SCHEMBL1408706 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL27754978 | 0.76 | MEN1 (0.47) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL21798510 | 0.74 | NOTUM (0.50) | ALDH1A1MEN1KMT2ANOTUMTSHR | |
| SCHEMBL28213553 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL14156263 | 0.73 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL6769554 | 0.73 | MEN1 (0.46) | ALDH1A1MEN1KMT2AUSP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256326-B | Indoline carboxylic acid alkaloid in purslane and extraction and separation method and application thereof | 辽宁中医药大学 | 2022-05-13 | — | — | CN | claimed |
| CN-111646999-A | Indoline carboxylic acid compound and preparation method thereof | 内江师范学院 | 2020-09-11 | — | — | CN | claimed |
| US-20090253932-A1 | Resolution of Racemic Organic Acids with (1S, 4S)-4[3,4-Dichlorophenyl]-1,2,3,4-Tetrahydro-N-Methyl-1-Naphthaloneamine | MATRIX LABORATORIES LTD (IN) | 2009-10-08 | — | — | US | claimed |
| EP-1831132-A2 | RESOLUTION OF RACEMIC ORGANIC ACIDS WITH (1S, 4S)-4[3,4-DICHLOROPHENYL]-1,2,3,4- TETRAHYDRO-N-METHYL-1-NAPHTHALONEAMINE | Matrix Laboratories Ltd (IN) | 2007-09-12 | — | — | EP | claimed |
| WO-2006013581-A2 | RESOLUTION OF RACEMIC ORGANIC ACIDS WITH (1S, 4S)-4[3,4-DICHLOROPHENYL]-1,2,3,4- TETRAHYDRO-N-METHYL-1-NAPHTHALONEAMINE | MATRIX LABORATORIES LTD (IN) | 2006-02-09 | — | — | WO | claimed |
| US-6232305-B1 | ANTICANCER AGENTS; BONE DISORDERS; ANTIARTHRITIC AGENTS; RESPIRATORY SYSTEM DISORDERS | NAEJA PHARMACEUTICAL INC. (CA) | 2001-05-15 | — | — | US | claimed |
| JP-3204666-A | — | — | None | — | — | JP | disclosed |
| US-11964037-B2 | Hair-dyeing method | KAO CORPORATION (JP) | 2024-04-23 | — | — | US | disclosed |
| US-20230110875-A1 | ANTI-CD276 POLYPEPTIDES, PROTEINS, AND CHIMERIC ANTIGEN RECEPTORS | BIOMED VALLEY DISCOVERIES, INC. | 2023-04-13 | — | — | US | disclosed |
| US-20230048023-A1 | HAIR-DYEING METHOD | KAO CORPORATION (JP) | 2023-02-16 | — | — | US | disclosed |
| EP-4082620-A1 | HAIR-DYEING METHOD | Kao Corporation (JP) | 2022-11-02 | — | — | EP | disclosed |
| CN-114828817-A | Method for dyeing hair | 花王株式会社 | 2022-07-29 | — | — | CN | disclosed |
| CN-110256326-B | Indoline carboxylic acid alkaloid in purslane and extraction and separation method and application thereof | 辽宁中医药大学 | 2022-05-13 | — | — | CN | disclosed |
| US-4697016-A | Intermediates for the preparation of a carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0105919-B1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | disclosed |
| US-4595766-A | Process for the preparation of an indoline carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1986-06-17 | — | — | US | disclosed |
| US-4595766-A | Process for the preparation of an indoline carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1986-06-17 | — | — | US | disclosed |
| US-4493843-A | Indole and indoline carboxylic acid compounds and method of use | MAY & BAKER LIMITED (GB) | 1985-01-15 | — | — | US | disclosed |
| EP-0105919-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES. | CIBA GEIGY AG (CH) | 1984-04-25 | — | — | EP | disclosed |
| WO-1983003828-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253932-A1 | Resolution of Racemic Organic Acids with (1S, 4S)-4[3,4-Dichlorophenyl]-1,2,3,4-Tetrahydro-N-Methyl-1-Naphthaloneamine | HTR4, OXER1, CYP2S1 | ALDH1A1 464/4885MEN1 1897/4885KMT2A 2489/4885 |
| US-11964037-B2 | Hair-dyeing method | KAT7, KAT2B, SRD5A1 | ALDH1A1 25/4885MEN1 2278/4885KMT2A 824/4885 |
| US-20230048023-A1 | HAIR-DYEING METHOD | KAT7, KAT2B, SRD5A1 | ALDH1A1 25/4885MEN1 2278/4885KMT2A 824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.