Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088593 | 0.87 | HTT (0.47) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL5952860 | 0.85 | HTT (0.41) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL5961872 | 0.85 | HTT (0.48) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL14088590 | 0.84 | HTT (0.56) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL14088565 | 0.82 | THRB (0.41) | HTTPOLBNPC1LMNANFKB1 | |
| SCHEMBL5844203 | 0.81 | POLB (0.58) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL16133504 | 0.81 | NPC1 (0.51) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL13991607 | 0.80 | HTT (0.41) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL12731196 | 0.79 | NPC1 (0.51) | HTTPOLBAPEX1TDP1NPC1 | |
| SCHEMBL14088404 | 0.79 | RXRA (0.36) | POLBKMT2AMAPTRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |