SCHEMBL14090779

SCHEMBL14090779

CO[Si](CCCNC(=O)Nc1ccc(P(=O)(O)O)cc1)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.42
EPHX1 P07099 4/20 0.42
ALDH1A1 P00352 2/20 0.42
HTT P42858 1/20 0.42
FPR2 P25090 4/20 0.41
CNR1 P21554 2/20 0.41
CASR P41180 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDR P35968 1/20 0.41
QPCT Q16769 1/20 0.41
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16804335 0.88 KMT2A (0.48) LMNASMN1; SMN2EPHX1ALDH1A1HTT
SCHEMBL16804337 0.85 SMN1; SMN2 (0.46) LMNASMN1; SMN2FPR2CNR1CASR
SCHEMBL23583705 0.82 SAE1 (0.57) LMNASMN1; SMN2EPHX1ALDH1A1HTT
SCHEMBL17133246 0.82 LMNA (0.65) LMNASMN1; SMN2EPHX1ALDH1A1HTT
SCHEMBL17030472 0.81 KEAP1 (0.54) LMNASMN1; SMN2ALDH1A1QPCTMAPT
SCHEMBL28415484 0.78 LMNA (0.68) LMNAEPHX1ALDH1A1HTTFPR2
SCHEMBL17133268 0.75 LMNA (0.56) LMNASMN1; SMN2EPHX1ALDH1A1HTT
SCHEMBL21581791 0.75 EPHX1 (0.51) LMNAEPHX1ALDH1A1HTTCYP1A2
SCHEMBL17030476 0.74 CDK2 (0.72) FPR2MAPT
SCHEMBL8549984 0.74 EPHX1 (0.43) LMNAEPHX1ALDH1A1HTTCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207849-A1 HYDROPHILIC FILM FORMING COMPOSITION AND HYDROPHILIC MEMBER FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed