SCHEMBL14093786

SCHEMBL14093786

CN1C(=Cc2c(S)c(=O)c2=O)C(C)(C)c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 0.55
HTT P42858 6/20 0.55
MAPT P10636 13/20 0.50
MEN1 O00255 10/20 0.50
KMT2A Q03164 10/20 0.50
USP2 O75604 4/20 0.50
TSHR P16473 3/20 0.49
THRB P10828 3/20 0.49
RECQL P46063 3/20 0.49
KDM4E B2RXH2 6/20 0.48
ALDH1A1 P00352 5/20 0.48
GAA P10253 4/20 0.48
POLB P06746 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
HSD17B10 Q99714 2/20 0.48
CASP1 P29466 2/20 0.48
MAPK1 P28482 4/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3853022 0.83 LMNA (0.55) LMNAHTTMAPTMEN1KMT2A
SCHEMBL3853014 0.83 LMNA (0.55) LMNAHTTMAPTMEN1KMT2A
SCHEMBL17627872 0.82 LMNA (0.54) LMNAHTTMAPTMEN1KMT2A
SCHEMBL7701823 0.81 LMNA (0.52) LMNAHTTMAPTMEN1KMT2A
SCHEMBL7701821 0.81 LMNA (0.52) LMNAHTTMAPTMEN1KMT2A
SCHEMBL14453270 0.76 MAPT (0.52) LMNAHTTMAPTMEN1KMT2A
SCHEMBL5522293 0.76 MAPT (0.52) LMNAHTTMAPTMEN1KMT2A
SCHEMBL19815786 0.75 MAPT (0.48) LMNAHTTMAPTMEN1KMT2A
SCHEMBL5515255 0.75 MAPT (0.48) LMNAHTTMAPTMEN1KMT2A
SCHEMBL11246520 0.72 LMNA (0.55) LMNAHTTMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9841428-B2 Viscosity-sensitive dyes and method SETA BIOMEDICALS, LLC (US) 2017-12-12 US disclosed
US-9841428-B2 Viscosity-sensitive dyes and method SETA BIOMEDICALS, LLC (US) 2017-12-12 US disclosed
US-20160091495-A1 VISCOSITY-SENSITIVE DYES AND METHOD SETA BIOMEDICALS, LLC 2016-03-31 US disclosed
US-20160091495-A1 VISCOSITY-SENSITIVE DYES AND METHOD SETA BIOMEDICALS, LLC 2016-03-31 US disclosed
US-7411068-B2 Luminescent compounds SETA BIOMEDICALS, LLC 2008-08-12 US disclosed
US-7411068-B2 Luminescent compounds SETA BIOMEDICALS, LLC 2008-08-12 US disclosed
US-7250517-B2 Luminescent compounds Terpetschnig, Ewald A. (US) 2007-07-31 US disclosed
US-7250517-B2 Luminescent compounds Terpetschnig, Ewald A. (US) 2007-07-31 US disclosed