Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 12/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701821 | 1.00 | LMNA (0.52) | LMNAHTTMAPTALDH1A1GAA | |
| SCHEMBL5515255 | 0.83 | MAPT (0.48) | LMNAHTTMAPTALDH1A1GAA | |
| SCHEMBL19815786 | 0.83 | MAPT (0.48) | LMNAHTTMAPTALDH1A1GAA | |
| SCHEMBL3853022 | 0.81 | LMNA (0.55) | LMNAHTTMAPTALDH1A1GAA | |
| SCHEMBL3853014 | 0.81 | LMNA (0.55) | LMNAHTTMAPTALDH1A1GAA | |
| SCHEMBL14093786 | 0.81 | LMNA (0.55) | LMNAHTTMAPTALDH1A1GAA | |
| SCHEMBL17627872 | 0.80 | LMNA (0.54) | LMNAHTTMAPTALDH1A1GAA | |
| SCHEMBL14093787 | 0.76 | MAPT (0.51) | LMNAHTTMAPTALDH1A1GAA | |
| SCHEMBL3468060 | 0.74 | MAPT (0.45) | LMNAHTTMAPTALDH1A1GAA | |
| SCHEMBL3468065 | 0.74 | MAPT (0.45) | LMNAHTTMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165693-A2 | SQUARAINE DYES | Amersham Pharmacia Biotech UK Limited (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058405-A2 | SQUARAINE DYES | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |