Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17445961 | 0.92 | L3MBTL1 (0.35) | MEN1KMT2AOPRM1MAPTALDH1A1 | |
| SCHEMBL14095018 | 0.79 | ALDH1A1 (0.33) | POLBALDH1A1HPGDCYP2C19 | |
| SCHEMBL17445964 | 0.79 | GLO1 (0.38) | MEN1KMT2APOLBDHODHMAPT | |
| SCHEMBL21128883 | 0.79 | GLO1 (0.38) | MEN1KMT2APOLBDHODHMAPT | |
| SCHEMBL14015982 | 0.77 | CYP3A4 (0.34) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL17445954 | 0.74 | MAPT (0.55) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL21128880 | 0.74 | ALDH1A1 (0.39) | MEN1KMT2AOPRM1MAPTALDH1A1 | |
| SCHEMBL17447694 | 0.74 | ALDH1A1 (0.39) | MEN1KMT2AOPRM1MAPTALDH1A1 | |
| SCHEMBL14015981 | 0.69 | HTT (0.31) | MEN1KMT2ATSHRGAAL3MBTL1 | |
| SCHEMBL17445965 | 0.68 | PRKCA (0.33) | POLBALDH1A1HPGDTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7407648-B2 | Merocyanine derivatives for cosmetic use | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-08-05 | — | — | US | disclosed |