Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 4/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478077 | 0.91 | PDE4B (0.35) | PDE4BHTR2BCNR2CASP3SENP8 | |
| SCHEMBL14077224 | 0.80 | HPGD (0.47) | CNR2LMNACYP2C19HPGDKDM4E | |
| SCHEMBL15303999 | 0.78 | TLR8 (0.45) | CNR2SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL14077225 | 0.78 | ALDH1A1 (0.46) | CNR2SMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL14077222 | 0.77 | TLR8 (0.47) | CNR2SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL3046300 | 0.77 | RXRA (0.46) | CNR2SMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL3043543 | 0.76 | RXRA (0.45) | CNR2SMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL3043550 | 0.76 | RXRA (0.45) | CNR2SMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL3043546 | 0.75 | IKBKB (0.40) | PDE4BCNR2IKBKB | |
| SCHEMBL9440928 | 0.71 | LTA4H (0.42) | SMN1; SMN2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214448-A1 | Compounds, Methods and Formulations for the Oral Delivery of a Glucagon-Like Peptide (Glp)-1 Compound or a Melanocortin-4 Receptor (Mc4) Agonist Peptide | EMISPHERE TECHNOLOGIES INC. (US) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214448-A1 | Compounds, Methods and Formulations for the Oral Delivery of a Glucagon-Like Peptide (Glp)-1 Compound or a Melanocortin-4 Receptor (Mc4) Agonist Peptide | MC4R, GLP1R, MC3R | PDE4B 384/4885HTR2B 281/4885CNR2 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.