Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 10/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14096265 | 0.86 | TP53 (0.52) | ALDH1A1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14096260 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPK1FAAHPTGESMAPT | |
| SCHEMBL14137239 | 0.80 | MAPT (0.49) | ALDH1A1MAPK1PTGESMAPTNPC1 | |
| SCHEMBL4360192 | 0.79 | PTGES (0.47) | ALDH1A1MAPK1FAAHPTGESMAPT | |
| SCHEMBL4361488 | 0.78 | MAPT (0.47) | ALDH1A1FAAHPTGESMAPTKDM4E | |
| SCHEMBL27803833 | 0.78 | LMNA (0.53) | FAAHMAPTKDM4EHPGDHTT | |
| SCHEMBL4361364 | 0.78 | ALDH1A1 (0.60) | ALDH1A1FAAHPTGESMAPTKDM4E | |
| SCHEMBL14096058 | 0.77 | SMN1; SMN2 (0.57) | ALDH1A1PTGESMAPTNPC1RAB9A | |
| SCHEMBL2858909 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPK1FAAHPTGESMAPT | |
| SCHEMBL4368032 | 0.77 | MAPT (0.53) | ALDH1A1MAPK1FAAHPTGESMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | RNASE1, SARS1, EIF2AK2 | ALDH1A1 2930/4885MAPK1 4584/4885FAAH 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.